Corpus callosum length by gestational age as evaluated by fetal MR imaging

Julie H. Harreld, R. Bhore, D. P. Chason, D. M. Twickler

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Although suspected corpus callosum abnormality is a common indication for fetal MR imaging, biometric data specific to MR imaging are sparse. We sought to characterize growth in corpus callosum length by EGA with fetal MR imaging. Corpus callosum segments were assessed and overall corpus callosum length was measured and plotted against the EGA for 68 anatomically normal fetal brains ranging in EGA from 18.5 to 37.7 weeks, and linear and polynomial regression models were calculated. The body of the corpus callosum was identified in all fetuses, followed in frequency by the splenium (91.2%), genu (85.3%), and rostrum (32.4%). Measurements of corpus callosum length by MR imaging were in agreement with values established by sonography. A second-degree polynomial function was the best fit for callosal length by EGA. Understanding this normal growth pattern may enhance detection of subtle growth abnormalities.

Original languageEnglish (US)
Pages (from-to)490-494
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume32
Issue number3
DOIs
StatePublished - Mar 1 2011

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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