Correction to: Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model (Protein & Cell, (2021), 12, 10, (769-787), 10.1007/s13238-021-00858-3)

Xiaoyan Xu, Yaqin Sun, Xufeng Cen, Bing Shan, Qingwei Zhao, Tingxue Xie, Zhe Wang, Tingjun Hou, Yu Xue, Mengmeng Zhang, Di Peng, Qiming Sun, Cong Yi, Ayaz Najafov, Hongguang Xia

Research output: Contribution to journalComment/debatepeer-review

Abstract

In legend of figure 1, this sentence “(C) 293THK cells were treated as in a” should be corrected as “(C) 293THK cells were treated as in (A)”. In legend of figure 2, “E-64D (10 μmol/L)” in description of panel (B) should be removed. In section “Metformin activates chaperone-mediated autophagy” of RESULTS, E-64D in sentence “Metformininduced degradation of HK2 and PKM2 was blocked by lysosomal inhibitors (E-64D, Bafilomycin A1 and Leupeptin + NH4Cl)” should be removed. The word “upon” in the sentence “Moreover, the activation of astrocytes in the hippocampus, as judged by GFAP staining, was also reduced upon following Metformin treatment (Fig. 6C)” should be removed. The correct Fig. 2 is shown below.

Original languageEnglish (US)
Pages (from-to)227-229
Number of pages3
JournalProtein and Cell
Volume13
Issue number3
DOIs
StatePublished - Mar 2022
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Drug Discovery
  • Cell Biology

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