Abstract
Diffusion Tensor Imaging (DTI) uses single shell gradient encoding scheme for studying brain tissue diffusion. NODDI (Neurite Orientation Dispersion and Density Imaging) incorporates a gradient scheme with multiple b-values which is used to characterize neurite density and coherence of neuron fiber orientations. Similarly, the diffusion kurtosis imaging also uses a multiple shell scheme to quantify non-Gaussian diffusion but does not assume a tissue model like NODDI. In this study we investigate the connection between metrics used by NODDI and DKI in children with ages from 46 weeks to 6 years. We correlate the NODDI metrics and Kurtosis measures from the same ROIs in multiple brain regions. We compare the range of these metrics between neonates (46 - 47 weeks), infants (2 -10 months) and young children (2 - 6 years).
Original language | English (US) |
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Title of host publication | Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging |
Publisher | SPIE |
Volume | 9788 |
ISBN (Electronic) | 9781510600232 |
DOIs | |
State | Published - 2016 |
Event | Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging - San Diego, United States Duration: Mar 1 2016 → Mar 3 2016 |
Other
Other | Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging |
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Country/Territory | United States |
City | San Diego |
Period | 3/1/16 → 3/3/16 |
Keywords
- Correlation
- DTI
- Kurtosis imaging
- Neonates
- NODDI
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging