Abstract
Diffusion Tensor Imaging (DTI) uses single shell gradient encoding scheme for studying brain tissue diffusion. NODDI (Neurite Orientation Dispersion and Density Imaging) incorporates a gradient scheme with multiple b-values which is used to characterize neurite density and coherence of neuron fiber orientations. Similarly, the diffusion kurtosis imaging also uses a multiple shell scheme to quantify non-Gaussian diffusion but does not assume a tissue model like NODDI. In this study we investigate the connection between metrics used by NODDI and DKI in children with ages from 46 weeks to 6 years. We correlate the NODDI metrics and Kurtosis measures from the same ROIs in multiple brain regions. We compare the range of these metrics between neonates (46 - 47 weeks), infants (2 -10 months) and young children (2 - 6 years).
| Original language | English (US) |
|---|---|
| Title of host publication | Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging |
| Publisher | SPIE |
| Volume | 9788 |
| ISBN (Electronic) | 9781510600232 |
| DOIs | |
| State | Published - 2016 |
| Event | Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging - San Diego, United States Duration: Mar 1 2016 → Mar 3 2016 |
Other
| Other | Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging |
|---|---|
| Country | United States |
| City | San Diego |
| Period | 3/1/16 → 3/3/16 |
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Keywords
- Correlation
- DTI
- Kurtosis imaging
- Neonates
- NODDI
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Correlation between diffusion kurtosis and NODDI metrics in neonates and young children. / Ahmed, Shaheen; Wang, Zhiyue J.; Chia, Jonathan M.; Rollins, Nancy K.
Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 9788 SPIE, 2016. 97881F.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Correlation between diffusion kurtosis and NODDI metrics in neonates and young children
AU - Ahmed, Shaheen
AU - Wang, Zhiyue J.
AU - Chia, Jonathan M.
AU - Rollins, Nancy K.
PY - 2016
Y1 - 2016
N2 - Diffusion Tensor Imaging (DTI) uses single shell gradient encoding scheme for studying brain tissue diffusion. NODDI (Neurite Orientation Dispersion and Density Imaging) incorporates a gradient scheme with multiple b-values which is used to characterize neurite density and coherence of neuron fiber orientations. Similarly, the diffusion kurtosis imaging also uses a multiple shell scheme to quantify non-Gaussian diffusion but does not assume a tissue model like NODDI. In this study we investigate the connection between metrics used by NODDI and DKI in children with ages from 46 weeks to 6 years. We correlate the NODDI metrics and Kurtosis measures from the same ROIs in multiple brain regions. We compare the range of these metrics between neonates (46 - 47 weeks), infants (2 -10 months) and young children (2 - 6 years).
AB - Diffusion Tensor Imaging (DTI) uses single shell gradient encoding scheme for studying brain tissue diffusion. NODDI (Neurite Orientation Dispersion and Density Imaging) incorporates a gradient scheme with multiple b-values which is used to characterize neurite density and coherence of neuron fiber orientations. Similarly, the diffusion kurtosis imaging also uses a multiple shell scheme to quantify non-Gaussian diffusion but does not assume a tissue model like NODDI. In this study we investigate the connection between metrics used by NODDI and DKI in children with ages from 46 weeks to 6 years. We correlate the NODDI metrics and Kurtosis measures from the same ROIs in multiple brain regions. We compare the range of these metrics between neonates (46 - 47 weeks), infants (2 -10 months) and young children (2 - 6 years).
KW - Correlation
KW - DTI
KW - Kurtosis imaging
KW - Neonates
KW - NODDI
UR - http://www.scopus.com/inward/record.url?scp=84978832813&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84978832813&partnerID=8YFLogxK
U2 - 10.1117/12.2217197
DO - 10.1117/12.2217197
M3 - Conference contribution
AN - SCOPUS:84978832813
VL - 9788
BT - Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
PB - SPIE
ER -