Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.
|Original language||English (US)|
|Number of pages||2|
|Journal||Infection and Immunity|
|State||Published - Dec 1998|
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