Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

Andrew B. Onderdonk; James A. Richardson; Robert E. Hammer; Joel D. Taurog

doi:10.1128/iai.66.12.6022-6023.1998

Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

Andrew B. Onderdonk, James A. Richardson, Robert E. Hammer, Joel D. Taurog

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.

Original language	English (US)
Pages (from-to)	6022-6023
Number of pages	2
Journal	Infection and immunity
Volume	66
Issue number	12
DOIs	https://doi.org/10.1128/iai.66.12.6022-6023.1998
State	Published - Dec 1998

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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