Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

Andrew B. Onderdonk, James A. Richardson, Robert E. Hammer, Joel D. Taurog

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.

Original languageEnglish (US)
Pages (from-to)6022-6023
Number of pages2
JournalInfection and immunity
Volume66
Issue number12
DOIs
StatePublished - Dec 1998

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease'. Together they form a unique fingerprint.

Cite this