Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

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Abstract

Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.

Original languageEnglish (US)
Pages (from-to)6022-6023
Number of pages2
JournalInfection and Immunity
Volume66
Issue number12
StatePublished - Dec 1998

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ASJC Scopus subject areas

  • Immunology

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