Correlation of preoperative deformity magnitude and pulmonary function tests in adolescent idiopathic scoliosis

Charles E. Johnston, B. Stephens Richards, Daniel J. Sucato, Keith H. Bridwell, Lawrence G. Lenke, Mark Erickson

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Study Design. Clinical study correlating preoperative pulmonary function tests (PFTs) to radiographic measures of thoracic deformity severity in adolescent idiopathic scoliosis (AIS) patients. Objective. To determine (1) the incidence of clinically relevant (<65% predicted value) pulmonary impairment in AIS patients; (2) if patients with more severe deformity have greater impairment of PFTs than those with lesser deformity; (3) the effect, if any, of juvenile onset deformity (onset < age 10) on preoperative PFTs. Summary of Background Data. Patients with late-onset (adolescent) spinal deformity are generally believed to have no respiratory morbidity except in severe curves exceeding 100°. Methods. A large multicenter database of surgically treated AIS patients with Lenke 1 to Lenke 4 curves was queried to report preoperative PFTs and correlate them with radiographic measures of coronal, sagittal, and axial plane deformities. Results. Nineteen percent of 858 patients had <65% predicted forced expiratory volume in 1 second (FEV1 ) and forced vital capacity (FVC) before surgery, and had larger main thoracic (MT) curves and greater axial rotation than those with predicted PFT values >65%. Patients with MT curves >70°, and especially >80°; proximal thoracic (PT) curves which were >30° or structural; or T5-T12 kyphosis <10° had significantly(P ≤ 0.001) lower FEV1 or FVC compared to those with less deformity. Axial plane deformity did not correlate with PFT impairment. Juvenile-onset patients had greater PFT impairment than AIS patients, along with slightly larger MT curves. Patients who were braced before surgery had worse PFTs than those had no treatment before surgery. Conclusion. Preoperative PFTs are clinically impaired in 19% of AIS patients, and correlate significantly with the MT and sagittal plane deformity severity, and with PT curve severity to a lesser degree. PFTs do not correlate with degree of axial deformity. From a purely pulmonary standpoint, attention directed to coronal and sagittal plane deformity correction appears warranted, to address the specific deformities which are associated with PFT impairment.

Original languageEnglish (US)
Pages (from-to)1096-1102
Number of pages7
JournalSpine
Volume36
Issue number14
DOIs
StatePublished - Jun 15 2011

Fingerprint

Respiratory Function Tests
Scoliosis
Thorax
Kyphosis
Lung
Incidence

Keywords

  • Adolescent idiopathic scoliosis
  • Impaired pulmonary function
  • Thoracic coronal and sagittal plane deformity

ASJC Scopus subject areas

  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

Correlation of preoperative deformity magnitude and pulmonary function tests in adolescent idiopathic scoliosis. / Johnston, Charles E.; Stephens Richards, B.; Sucato, Daniel J.; Bridwell, Keith H.; Lenke, Lawrence G.; Erickson, Mark.

In: Spine, Vol. 36, No. 14, 15.06.2011, p. 1096-1102.

Research output: Contribution to journalArticle

@article{89a981b85a4643f487938ea9908d9f68,
title = "Correlation of preoperative deformity magnitude and pulmonary function tests in adolescent idiopathic scoliosis",
abstract = "Study Design. Clinical study correlating preoperative pulmonary function tests (PFTs) to radiographic measures of thoracic deformity severity in adolescent idiopathic scoliosis (AIS) patients. Objective. To determine (1) the incidence of clinically relevant (<65{\%} predicted value) pulmonary impairment in AIS patients; (2) if patients with more severe deformity have greater impairment of PFTs than those with lesser deformity; (3) the effect, if any, of juvenile onset deformity (onset < age 10) on preoperative PFTs. Summary of Background Data. Patients with late-onset (adolescent) spinal deformity are generally believed to have no respiratory morbidity except in severe curves exceeding 100°. Methods. A large multicenter database of surgically treated AIS patients with Lenke 1 to Lenke 4 curves was queried to report preoperative PFTs and correlate them with radiographic measures of coronal, sagittal, and axial plane deformities. Results. Nineteen percent of 858 patients had <65{\%} predicted forced expiratory volume in 1 second (FEV1 ) and forced vital capacity (FVC) before surgery, and had larger main thoracic (MT) curves and greater axial rotation than those with predicted PFT values >65{\%}. Patients with MT curves >70°, and especially >80°; proximal thoracic (PT) curves which were >30° or structural; or T5-T12 kyphosis <10° had significantly(P ≤ 0.001) lower FEV1 or FVC compared to those with less deformity. Axial plane deformity did not correlate with PFT impairment. Juvenile-onset patients had greater PFT impairment than AIS patients, along with slightly larger MT curves. Patients who were braced before surgery had worse PFTs than those had no treatment before surgery. Conclusion. Preoperative PFTs are clinically impaired in 19{\%} of AIS patients, and correlate significantly with the MT and sagittal plane deformity severity, and with PT curve severity to a lesser degree. PFTs do not correlate with degree of axial deformity. From a purely pulmonary standpoint, attention directed to coronal and sagittal plane deformity correction appears warranted, to address the specific deformities which are associated with PFT impairment.",
keywords = "Adolescent idiopathic scoliosis, Impaired pulmonary function, Thoracic coronal and sagittal plane deformity",
author = "Johnston, {Charles E.} and {Stephens Richards}, B. and Sucato, {Daniel J.} and Bridwell, {Keith H.} and Lenke, {Lawrence G.} and Mark Erickson",
year = "2011",
month = "6",
day = "15",
doi = "10.1097/BRS.0b013e3181f8c931",
language = "English (US)",
volume = "36",
pages = "1096--1102",
journal = "Spine",
issn = "0362-2436",
publisher = "Lippincott Williams and Wilkins",
number = "14",

}

TY - JOUR

T1 - Correlation of preoperative deformity magnitude and pulmonary function tests in adolescent idiopathic scoliosis

AU - Johnston, Charles E.

AU - Stephens Richards, B.

AU - Sucato, Daniel J.

AU - Bridwell, Keith H.

AU - Lenke, Lawrence G.

AU - Erickson, Mark

PY - 2011/6/15

Y1 - 2011/6/15

N2 - Study Design. Clinical study correlating preoperative pulmonary function tests (PFTs) to radiographic measures of thoracic deformity severity in adolescent idiopathic scoliosis (AIS) patients. Objective. To determine (1) the incidence of clinically relevant (<65% predicted value) pulmonary impairment in AIS patients; (2) if patients with more severe deformity have greater impairment of PFTs than those with lesser deformity; (3) the effect, if any, of juvenile onset deformity (onset < age 10) on preoperative PFTs. Summary of Background Data. Patients with late-onset (adolescent) spinal deformity are generally believed to have no respiratory morbidity except in severe curves exceeding 100°. Methods. A large multicenter database of surgically treated AIS patients with Lenke 1 to Lenke 4 curves was queried to report preoperative PFTs and correlate them with radiographic measures of coronal, sagittal, and axial plane deformities. Results. Nineteen percent of 858 patients had <65% predicted forced expiratory volume in 1 second (FEV1 ) and forced vital capacity (FVC) before surgery, and had larger main thoracic (MT) curves and greater axial rotation than those with predicted PFT values >65%. Patients with MT curves >70°, and especially >80°; proximal thoracic (PT) curves which were >30° or structural; or T5-T12 kyphosis <10° had significantly(P ≤ 0.001) lower FEV1 or FVC compared to those with less deformity. Axial plane deformity did not correlate with PFT impairment. Juvenile-onset patients had greater PFT impairment than AIS patients, along with slightly larger MT curves. Patients who were braced before surgery had worse PFTs than those had no treatment before surgery. Conclusion. Preoperative PFTs are clinically impaired in 19% of AIS patients, and correlate significantly with the MT and sagittal plane deformity severity, and with PT curve severity to a lesser degree. PFTs do not correlate with degree of axial deformity. From a purely pulmonary standpoint, attention directed to coronal and sagittal plane deformity correction appears warranted, to address the specific deformities which are associated with PFT impairment.

AB - Study Design. Clinical study correlating preoperative pulmonary function tests (PFTs) to radiographic measures of thoracic deformity severity in adolescent idiopathic scoliosis (AIS) patients. Objective. To determine (1) the incidence of clinically relevant (<65% predicted value) pulmonary impairment in AIS patients; (2) if patients with more severe deformity have greater impairment of PFTs than those with lesser deformity; (3) the effect, if any, of juvenile onset deformity (onset < age 10) on preoperative PFTs. Summary of Background Data. Patients with late-onset (adolescent) spinal deformity are generally believed to have no respiratory morbidity except in severe curves exceeding 100°. Methods. A large multicenter database of surgically treated AIS patients with Lenke 1 to Lenke 4 curves was queried to report preoperative PFTs and correlate them with radiographic measures of coronal, sagittal, and axial plane deformities. Results. Nineteen percent of 858 patients had <65% predicted forced expiratory volume in 1 second (FEV1 ) and forced vital capacity (FVC) before surgery, and had larger main thoracic (MT) curves and greater axial rotation than those with predicted PFT values >65%. Patients with MT curves >70°, and especially >80°; proximal thoracic (PT) curves which were >30° or structural; or T5-T12 kyphosis <10° had significantly(P ≤ 0.001) lower FEV1 or FVC compared to those with less deformity. Axial plane deformity did not correlate with PFT impairment. Juvenile-onset patients had greater PFT impairment than AIS patients, along with slightly larger MT curves. Patients who were braced before surgery had worse PFTs than those had no treatment before surgery. Conclusion. Preoperative PFTs are clinically impaired in 19% of AIS patients, and correlate significantly with the MT and sagittal plane deformity severity, and with PT curve severity to a lesser degree. PFTs do not correlate with degree of axial deformity. From a purely pulmonary standpoint, attention directed to coronal and sagittal plane deformity correction appears warranted, to address the specific deformities which are associated with PFT impairment.

KW - Adolescent idiopathic scoliosis

KW - Impaired pulmonary function

KW - Thoracic coronal and sagittal plane deformity

UR - http://www.scopus.com/inward/record.url?scp=79959956345&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959956345&partnerID=8YFLogxK

U2 - 10.1097/BRS.0b013e3181f8c931

DO - 10.1097/BRS.0b013e3181f8c931

M3 - Article

C2 - 21270699

AN - SCOPUS:79959956345

VL - 36

SP - 1096

EP - 1102

JO - Spine

JF - Spine

SN - 0362-2436

IS - 14

ER -