@article{96b22ce99da64d439866123e2b09854b,
title = "Cortical Map Plasticity Improves Learning but Is Not Necessary for Improved Performance",
abstract = "Cortical map plasticity is believed to be a key substrate of perceptual and skill learning. In the current study, we quantified changes in perceptual ability after pairing tones with stimulation of the cholinergic nucleus basalis to induce auditory cortex map plasticity outside of a behavioral context. Our results provide evidence that cortical map plasticity can enhance perceptual learning. However, auditory cortex map plasticity fades over weeks even though tone discrimination performance remains stable. This observation is consistent with recent reports that cortical map expansions associated with perceptual and motor learning are followed by a period of map renormalization without a decrement in performance. Our results indicate that cortical map plasticity enhances perceptual learning, but is not necessary to maintain improved discriminative ability.",
author = "Amanda Reed and Jonathan Riley and Ryan Carraway and Andres Carrasco and Claudia Perez and Vikram Jakkamsetti and Kilgard, {Michael P.}",
note = "Funding Information: This work was supported by the James S. McDonnell Foundation. The authors would like to thank the many undergraduate volunteers who contributed to data collection and would like to thank Nick Reed, Crystal Engineer, Navzer Engineer, Kamalini Ranasinghe, Jai Shetake, and Benjamin Porter for comments on the manuscript. We would also like to thank Bernhard Gaese, Jonathan Fritz, Dan Polley, Dean Buonomano, Jan Schnupp, and Alice O'Toole for their useful discussions about the project and manuscript. Author contributions were as follows: A.R., J.R., R.C., M.K., and A.C. all contributed to experimental design. A.R., J.R., R.C., C.P., and A.C. collected data, and V.J. and M.K. performed surgical procedures. A.R., J.R., and A.C. performed data analysis, and A.R. and M.K. wrote and prepared the manuscript. All authors read and commented on the manuscript. ",
year = "2011",
month = apr,
day = "14",
doi = "10.1016/j.neuron.2011.02.038",
language = "English (US)",
volume = "70",
pages = "121--131",
journal = "Neuron",
issn = "0896-6273",
publisher = "Cell Press",
number = "1",
}