CRISPR/Cas9 and TALE: beyond cut and paste

Liping Deng, Ruotong Ren, Jun Wu, Keiichiro Suzuki, Juan Carlos Izpisua Belmote, Guang Hui Liu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal structures or genomic regions.

Original languageEnglish (US)
Pages (from-to)157-159
Number of pages3
JournalProtein and Cell
Volume6
Issue number3
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Clustered Regularly Interspaced Short Palindromic Repeats
Gene therapy
Regulator Genes
Ointments
Gene expression
Genetic Therapy
Genes
Gene Expression
Gene Editing

Keywords

  • CRISPR/Cas9
  • gene expression
  • genome editing
  • TALE
  • transcription regulation

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Drug Discovery
  • Cell Biology

Cite this

Deng, L., Ren, R., Wu, J., Suzuki, K., Izpisua Belmote, J. C., & Liu, G. H. (2015). CRISPR/Cas9 and TALE: beyond cut and paste. Protein and Cell, 6(3), 157-159. https://doi.org/10.1007/s13238-015-0137-5

CRISPR/Cas9 and TALE : beyond cut and paste. / Deng, Liping; Ren, Ruotong; Wu, Jun; Suzuki, Keiichiro; Izpisua Belmote, Juan Carlos; Liu, Guang Hui.

In: Protein and Cell, Vol. 6, No. 3, 01.01.2015, p. 157-159.

Research output: Contribution to journalArticle

Deng, L, Ren, R, Wu, J, Suzuki, K, Izpisua Belmote, JC & Liu, GH 2015, 'CRISPR/Cas9 and TALE: beyond cut and paste', Protein and Cell, vol. 6, no. 3, pp. 157-159. https://doi.org/10.1007/s13238-015-0137-5
Deng L, Ren R, Wu J, Suzuki K, Izpisua Belmote JC, Liu GH. CRISPR/Cas9 and TALE: beyond cut and paste. Protein and Cell. 2015 Jan 1;6(3):157-159. https://doi.org/10.1007/s13238-015-0137-5
Deng, Liping ; Ren, Ruotong ; Wu, Jun ; Suzuki, Keiichiro ; Izpisua Belmote, Juan Carlos ; Liu, Guang Hui. / CRISPR/Cas9 and TALE : beyond cut and paste. In: Protein and Cell. 2015 ; Vol. 6, No. 3. pp. 157-159.
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