CSF somatostatin immunoreactivity and GH plasma levels in Alzheimer's disease

L. Steardo; C. A. Tamminga; P. Barone

CSF somatostatin immunoreactivity and GH plasma levels in Alzheimer's disease

L. Steardo, C. A. Tamminga, P. Barone

Research output: Contribution to journal › Article › peer-review

Abstract

Growth hormone (GH) plasma levels over 24 hours were studied in 9 subjects with Alzheimer's disease and in 8 healthy volunteers. No significant difference occurred between two groups. Conversely, levels of somatostatin immunoreactivity (SRIF-IR) were significantly lower in lumbar cerebrospinal fluid (CSF) of the patients compared to the controls, suggesting that the hypothalamus is relatively spared and the lack of any correlation between hypothalamic somatostatin and CSF SRIF-IR.

Original language	English (US)
Pages (from-to)	291-294
Number of pages	4
Journal	Neuroendocrinology Letters
Volume	6
Issue number	5
State	Published - Jan 1 1984

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Neurology
Endocrine and Autonomic Systems
Clinical Neurology
Psychiatry and Mental health

Cite this

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title = "CSF somatostatin immunoreactivity and GH plasma levels in Alzheimer's disease",

abstract = "Growth hormone (GH) plasma levels over 24 hours were studied in 9 subjects with Alzheimer's disease and in 8 healthy volunteers. No significant difference occurred between two groups. Conversely, levels of somatostatin immunoreactivity (SRIF-IR) were significantly lower in lumbar cerebrospinal fluid (CSF) of the patients compared to the controls, suggesting that the hypothalamus is relatively spared and the lack of any correlation between hypothalamic somatostatin and CSF SRIF-IR.",

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N2 - Growth hormone (GH) plasma levels over 24 hours were studied in 9 subjects with Alzheimer's disease and in 8 healthy volunteers. No significant difference occurred between two groups. Conversely, levels of somatostatin immunoreactivity (SRIF-IR) were significantly lower in lumbar cerebrospinal fluid (CSF) of the patients compared to the controls, suggesting that the hypothalamus is relatively spared and the lack of any correlation between hypothalamic somatostatin and CSF SRIF-IR.

AB - Growth hormone (GH) plasma levels over 24 hours were studied in 9 subjects with Alzheimer's disease and in 8 healthy volunteers. No significant difference occurred between two groups. Conversely, levels of somatostatin immunoreactivity (SRIF-IR) were significantly lower in lumbar cerebrospinal fluid (CSF) of the patients compared to the controls, suggesting that the hypothalamus is relatively spared and the lack of any correlation between hypothalamic somatostatin and CSF SRIF-IR.

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CSF somatostatin immunoreactivity and GH plasma levels in Alzheimer's disease

Abstract

ASJC Scopus subject areas

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