Cu-Catalyzed Decarboxylative Borylation

Jie Wang, Ming Shang, Helena Lundberg, Karla S. Feu, Scott J. Hecker, Tian Qin, Donna G. Blackmond, Phil S. Baran

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and operationally simple option. In addition to a full exploration of the scope, a kinetic study was performed to elucidate substrate and reagent concentration dependences.

Original languageEnglish (US)
Pages (from-to)9537-9542
Number of pages6
JournalACS Catalysis
Volume8
Issue number10
DOIs
StatePublished - Oct 5 2018
Externally publishedYes

Keywords

  • copper catalysis
  • decarboxylative borylation
  • kinetic studies
  • practical protocol
  • redox-active esters

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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  • Cite this

    Wang, J., Shang, M., Lundberg, H., Feu, K. S., Hecker, S. J., Qin, T., Blackmond, D. G., & Baran, P. S. (2018). Cu-Catalyzed Decarboxylative Borylation. ACS Catalysis, 8(10), 9537-9542. https://doi.org/10.1021/acscatal.8b02928