Current evidence supporting a goal of singletons: a review of maternal and perinatal outcomes associated with twin versus singleton pregnancies after in vitro fertilization and intracytoplasmic sperm injection

Abey Eapen; Ginny L. Ryan; Patrick Ten Eyck; Bradley J. Van Voorhis

doi:10.1016/j.fertnstert.2020.08.1423

Current evidence supporting a goal of singletons: a review of maternal and perinatal outcomes associated with twin versus singleton pregnancies after in vitro fertilization and intracytoplasmic sperm injection

Abey Eapen, Ginny L. Ryan, Patrick Ten Eyck, Bradley J. Van Voorhis

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

With increasing use of in vitro fertilization and intracytoplasmic sperm injection (IVF-ICSI) almost 2% of all babies born in the United States each year are now conceived with these technologies, making outcomes of IVF-ICSI extremely important not only to patients and families but to public health. Twin pregnancy rates after IVF-ICSI in the United States have declined since their peak in 2013 but remain at approximately 1 in 10 to 1 in 20 pregnancies. A review of the current international literature on twin versus singleton pregnancy outcomes after IVF-ICSI treatment confirms statistically significantly higher risks to maternal and perinatal health and statistically significantly higher health care costs. The field of infertility care should continue to work to develop practices that lower twin pregnancy rates to an absolute minimum to maximize the safety of these medical treatments.

Original language	English (US)
Pages (from-to)	690-714
Number of pages	25
Journal	Fertility and sterility
Volume	114
Issue number	4
DOIs	https://doi.org/10.1016/j.fertnstert.2020.08.1423
State	Published - Oct 2020
Externally published	Yes

Keywords

Health care costs
in vitro fertilization
infertility
maternal outcomes
multiple gestation pregnancy
perinatal outcomes
twins

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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Current evidence supporting a goal of singletons: a review of maternal and perinatal outcomes associated with twin versus singleton pregnancies after in vitro fertilization and intracytoplasmic sperm injection. / Eapen, Abey; Ryan, Ginny L.; Ten Eyck, Patrick et al.
In: Fertility and sterility, Vol. 114, No. 4, 10.2020, p. 690-714.

Research output: Contribution to journal › Review article › peer-review

Eapen, A, Ryan, GL, Ten Eyck, P & Van Voorhis, BJ 2020, 'Current evidence supporting a goal of singletons: a review of maternal and perinatal outcomes associated with twin versus singleton pregnancies after in vitro fertilization and intracytoplasmic sperm injection', Fertility and sterility, vol. 114, no. 4, pp. 690-714. https://doi.org/10.1016/j.fertnstert.2020.08.1423

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abstract = "With increasing use of in vitro fertilization and intracytoplasmic sperm injection (IVF-ICSI) almost 2% of all babies born in the United States each year are now conceived with these technologies, making outcomes of IVF-ICSI extremely important not only to patients and families but to public health. Twin pregnancy rates after IVF-ICSI in the United States have declined since their peak in 2013 but remain at approximately 1 in 10 to 1 in 20 pregnancies. A review of the current international literature on twin versus singleton pregnancy outcomes after IVF-ICSI treatment confirms statistically significantly higher risks to maternal and perinatal health and statistically significantly higher health care costs. The field of infertility care should continue to work to develop practices that lower twin pregnancy rates to an absolute minimum to maximize the safety of these medical treatments.",

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Current evidence supporting a goal of singletons: a review of maternal and perinatal outcomes associated with twin versus singleton pregnancies after in vitro fertilization and intracytoplasmic sperm injection

Abstract

Keywords

ASJC Scopus subject areas

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