Current progress in adaptive radiation therapy for head and neck cancer

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Head and neck intensity-modulated radiotherapy (IMRT) remains toxic, and cannot compensate for anatomic changes or tumor response that occur during treatment. Adaptive radiotherapy (ART) is a novel approach to correct for variations in geometry of tumor and bystander anatomy with repeated imaging-based modification of treatment delivery. Technical limitations have hampered introduction of ART into routine practice. This review summarizes investigationalchallenges impacting development of head and neck ART, describes findings from early clinical testing of an automated ART platform, and highlights emerging directions of ongoing research.

Original languageEnglish (US)
Pages (from-to)139-147
Number of pages9
JournalCurrent oncology reports
Volume14
Issue number2
DOIs
StatePublished - Apr 1 2012

Keywords

  • Adaptive radiotherapy
  • Clinical trial
  • Dosimetry
  • Head and neck cancer
  • IMRT
  • Image-guided

ASJC Scopus subject areas

  • Oncology

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