Cutaneous neoplastic manifestations of HIV disease

Cindy Berthelot, Clay J Cockerell

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

DEFINITION/OVERVIEW Kaposi’s sarcoma (KS) is the most frequent neoplastic disorder encountered in human immun - odeficiency virus (HIV)-infected patients, and was first described by Moritz Kaposi in 1872 as ‘idio - pathic, multiple, pigment sarcoma’.1 KS was con - sidered to be a relatively rare, slow-growing malig - nancy, most commonly seen in middle-aged and elderly men. However, this changed in 1981, with Alvin Friedman-Kein’s report of what eventually proved to be HIV-associated (epidemic) KS.1,2 This report described more than 50 previously healthy, young homosexual men with KS involving the lymph nodes, viscera, mucosa, and skin.2 Concurrent lifethreatening opportunistic infections were associated with profound immunosuppression, a syndrome now recognized as acquired immunodeficiency syndrome (AIDS). While the different KS subtypes run different clinical courses, what remains constant are the phenotypic features of the proliferating vascular elements (Table 10).

Original languageEnglish (US)
Title of host publicationCutaneous Manifestations of HIV Disease
PublisherCRC Press
Pages165-180
Number of pages16
ISBN (Electronic)9781840766042
ISBN (Print)9781840761429
DOIs
StatePublished - Jan 1 2012

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Skin Manifestations
Kaposi's Sarcoma
Virus Diseases
Viruses
Viscera
Opportunistic Infections
Immunosuppression
Blood Vessels
Mucous Membrane
Acquired Immunodeficiency Syndrome
Lymph Nodes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Berthelot, C., & Cockerell, C. J. (2012). Cutaneous neoplastic manifestations of HIV disease. In Cutaneous Manifestations of HIV Disease (pp. 165-180). CRC Press. https://doi.org/10.1201/b15910

Cutaneous neoplastic manifestations of HIV disease. / Berthelot, Cindy; Cockerell, Clay J.

Cutaneous Manifestations of HIV Disease. CRC Press, 2012. p. 165-180.

Research output: Chapter in Book/Report/Conference proceedingChapter

Berthelot, C & Cockerell, CJ 2012, Cutaneous neoplastic manifestations of HIV disease. in Cutaneous Manifestations of HIV Disease. CRC Press, pp. 165-180. https://doi.org/10.1201/b15910
Berthelot C, Cockerell CJ. Cutaneous neoplastic manifestations of HIV disease. In Cutaneous Manifestations of HIV Disease. CRC Press. 2012. p. 165-180 https://doi.org/10.1201/b15910
Berthelot, Cindy ; Cockerell, Clay J. / Cutaneous neoplastic manifestations of HIV disease. Cutaneous Manifestations of HIV Disease. CRC Press, 2012. pp. 165-180
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