Abstract
DEFINITION/OVERVIEW Kaposi’s sarcoma (KS) is the most frequent neoplastic disorder encountered in human immun - odeficiency virus (HIV)-infected patients, and was first described by Moritz Kaposi in 1872 as ‘idio - pathic, multiple, pigment sarcoma’.1 KS was con - sidered to be a relatively rare, slow-growing malig - nancy, most commonly seen in middle-aged and elderly men. However, this changed in 1981, with Alvin Friedman-Kein’s report of what eventually proved to be HIV-associated (epidemic) KS.1,2 This report described more than 50 previously healthy, young homosexual men with KS involving the lymph nodes, viscera, mucosa, and skin.2 Concurrent lifethreatening opportunistic infections were associated with profound immunosuppression, a syndrome now recognized as acquired immunodeficiency syndrome (AIDS). While the different KS subtypes run different clinical courses, what remains constant are the phenotypic features of the proliferating vascular elements (Table 10).
| Original language | English (US) |
|---|---|
| Title of host publication | Cutaneous Manifestations of HIV Disease |
| Publisher | CRC Press |
| Pages | 165-180 |
| Number of pages | 16 |
| ISBN (Electronic) | 9781840766042 |
| ISBN (Print) | 9781840761429 |
| DOIs | |
| State | Published - Jan 1 2012 |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
Cutaneous neoplastic manifestations of HIV disease. / Berthelot, Cindy; Cockerell, Clay J.
Cutaneous Manifestations of HIV Disease. CRC Press, 2012. p. 165-180.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Cutaneous neoplastic manifestations of HIV disease
AU - Berthelot, Cindy
AU - Cockerell, Clay J
PY - 2012/1/1
Y1 - 2012/1/1
N2 - DEFINITION/OVERVIEW Kaposi’s sarcoma (KS) is the most frequent neoplastic disorder encountered in human immun - odeficiency virus (HIV)-infected patients, and was first described by Moritz Kaposi in 1872 as ‘idio - pathic, multiple, pigment sarcoma’.1 KS was con - sidered to be a relatively rare, slow-growing malig - nancy, most commonly seen in middle-aged and elderly men. However, this changed in 1981, with Alvin Friedman-Kein’s report of what eventually proved to be HIV-associated (epidemic) KS.1,2 This report described more than 50 previously healthy, young homosexual men with KS involving the lymph nodes, viscera, mucosa, and skin.2 Concurrent lifethreatening opportunistic infections were associated with profound immunosuppression, a syndrome now recognized as acquired immunodeficiency syndrome (AIDS). While the different KS subtypes run different clinical courses, what remains constant are the phenotypic features of the proliferating vascular elements (Table 10).
AB - DEFINITION/OVERVIEW Kaposi’s sarcoma (KS) is the most frequent neoplastic disorder encountered in human immun - odeficiency virus (HIV)-infected patients, and was first described by Moritz Kaposi in 1872 as ‘idio - pathic, multiple, pigment sarcoma’.1 KS was con - sidered to be a relatively rare, slow-growing malig - nancy, most commonly seen in middle-aged and elderly men. However, this changed in 1981, with Alvin Friedman-Kein’s report of what eventually proved to be HIV-associated (epidemic) KS.1,2 This report described more than 50 previously healthy, young homosexual men with KS involving the lymph nodes, viscera, mucosa, and skin.2 Concurrent lifethreatening opportunistic infections were associated with profound immunosuppression, a syndrome now recognized as acquired immunodeficiency syndrome (AIDS). While the different KS subtypes run different clinical courses, what remains constant are the phenotypic features of the proliferating vascular elements (Table 10).
UR - http://www.scopus.com/inward/record.url?scp=85055496781&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85055496781&partnerID=8YFLogxK
U2 - 10.1201/b15910
DO - 10.1201/b15910
M3 - Chapter
AN - SCOPUS:85055496781
SN - 9781840761429
SP - 165
EP - 180
BT - Cutaneous Manifestations of HIV Disease
PB - CRC Press
ER -