Cutaneous venoarteriolar reflex alters 0.1 Hz fluctuations in skin blood flow

C. G. Crandall, R. A. Etzel

Research output: Contribution to journalArticle

Abstract

Skin blood flow (SkBF) fluctuations around 0.1 Hz are thought to be indicative of autonomic control of the cutaneous vasculature. The purpose of this study was to identify whether these fluctuations can be altered by the cutaneous venoarteriolar reflex. This reflex causes vasoconstriction via local mechanisms secondary to venous congestion. In 9 subjects SkBF was monitored on both forearms using laser-Doppler flowmetry [expressed in perfusion units (PU)]. While supine, and with both arms at heart level, each subject breathed at a rate of 0.25 Hz for 6 minutes. The venoarteriolar reflex was then engaged by lowering one arm (experimental) such that the laser-Doppler flow probe was 35±2 cm below heart level. The other arm (control) remained at heart level throughout the test. The aforementioned breathing protocol was repeated. The spectral power surrounding the low frequency peak (0.03 to 0.15 Hz) was not different between sites when both arms were at heart level (control: 652±146 PU2; experimental: 623±211 PU2, P>0.05), nor was there a difference in SkBF (control: 13.3±1.7 PU; experimental: 12.5±1.4 PU, P>0.05). Engagement of the venoarteriolar reflex in the experimental arm significantly reduced SkBF (control: 11.1±1.6 PU; experimental: 5.0±0.3 PU, P<0.05) and spectral power (control: 737±173 PU2; experimental: 73±71 PU2, P<0.05) in that arm. Reduced power of 0.1 Hz fluctuations in SkBF are likely due to increased vasomotor tone associated with the venoarteriolar reflex, thereby demonstrating that these fluctuations can be modified locally.

Original languageEnglish (US)
JournalFASEB Journal
Volume12
Issue number5
StatePublished - Mar 20 1998

Fingerprint

reflexes
skin (animal)
blood flow
Reflex
Skin
Blood
Arm
heart
Perfusion
Flow control
lasers
vasoconstriction
Lasers
Level control
Power control
probes (equipment)
breathing
Laser-Doppler Flowmetry
Hyperemia
Vasoconstriction

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Cite this

Cutaneous venoarteriolar reflex alters 0.1 Hz fluctuations in skin blood flow. / Crandall, C. G.; Etzel, R. A.

In: FASEB Journal, Vol. 12, No. 5, 20.03.1998.

Research output: Contribution to journalArticle

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