Cyclin A Turns on Bora to Light the Path to Mitosis

Ge Zheng, Hongtao Yu

Research output: Contribution to journalShort survey

2 Scopus citations

Abstract

Mitotic entry is an irreversible cell-cycle transition that requires the robust, rapid activation of cyclin-dependent kinase 1 (Cdk1). In this issue of Developmental Cell, Vigneron et al. (2018) identify cyclin A-Cdk1 as the factor triggering mitotic entry through the phosphorylation of Bora, an activator of the kinase Aurora A. Mitotic entry is an irreversible cell-cycle transition that requires the robust, rapid activation of cyclin-dependent kinase 1 (Cdk1). In this issue of Developmental Cell, Vigneron et al. (2018) identify cyclin A-Cdk1 as the factor triggering mitotic entry through the phosphorylation of Bora, an activator of the kinase Aurora A.

Original languageEnglish (US)
Pages (from-to)542-543
Number of pages2
JournalDevelopmental cell
Volume45
Issue number5
DOIs
StatePublished - Jun 4 2018

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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