Cylindrical spirals of myofilamentous origin associated with exertional cramps and rhabdomyolysis

Gil I. Wolfe, Dennis K. Burns, Daniel Krampitz, Richard J. Barohn

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

We describe the presence of cylindrical spirals on muscle biopsy from a 31-year-old man who developed rhabodomyolysis following a long run. He had a prior history of exertional cramps and myoglobinuria. His maternal grandfather had similar symptoms. Transmission electron micrographs demonstrated continuity between the lamellae of the cylindrical spirals and native myofilaments. Whether these unusual structures confer a derangement in myofilament function is uncertain.

Original languageEnglish (US)
Pages (from-to)536-538
Number of pages3
JournalNeuromuscular Disorders
Volume7
Issue number8
DOIs
StatePublished - Dec 1 1997

Keywords

  • Cramps
  • Cylindrical spirals
  • Myofilament

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Clinical Neurology
  • Genetics(clinical)

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