Cyproheptadine enhances the I_K of mouse cortical neurons through sigma-1 receptor-mediated intracellular signal pathway

Agriculture & Biology

• cyproheptadine 92%
• signal transduction 53%
• neurons 49%
• receptors 40%
• mice 34%
• serotonin receptors 13%
• antagonists 12%
• histamine 10%
• proteins 6%
• small interfering RNA 5%
• potassium channels 5%
• serotonin 4%
• agonists 4%
• electric potential difference 4%
• ligands 4%
• cells 3%
• assays 2%

Medicine & Life Sciences

• sigma-1 receptor 94%
• Cyproheptadine 85%
• Signal Transduction 46%
• Neurons 36%
• HEK293 Cells 10%
• Proteins 7%
• Histamine Receptors 6%
• Voltage-Gated Potassium Channels 6%
• Histamine H1 Receptors 6%
• Serotonin Antagonists 6%
• Histamine H2 Receptors 6%
• Serotonin Receptors 5%
• Serotonin 4%
• Small Interfering RNA 4%
• Ligands 3%

Chemical Compounds

• Cyproheptadine 100%
• Antagonist 12%
• Serotonergic Antagonist 10%
• Histamine Antagonist 9%
• Silencing RNA 8%
• Protein 8%
• Histamine 7%
• Agent Interacting With Transmitter, Hormone or Drug Receptor 7%
• Serotonin 7%