Arachidonic acid and many products of the arachidonate cascade serve as substrates for cytochrome P450-mediated metabolism via allylic oxidation, omega hydroxylation, and epoxygenation as well as peroxide rearrangement. Defining the physiological importance of these metabolites is an area of intense research interest. Cytochrome P450-catalyzed reactions play prominent roles in multiplying the structural and functional diversity of the arachidonate metabolic cascade.
|Original language||English (US)|
|Number of pages||6|
|State||Published - Jan 1 1992|
- Omega oxidation
- Prostanoids Hydroxyeicosatetraenoic acids
ASJC Scopus subject areas
- Molecular Biology