Cytokine expression by epidermal cell subpopulations

Hiroyuki Matsue, Ponciano D Cruz, Paul R. Bergstresser, Akira Takashima

Research output: Contribution to journalArticlepeer-review

76 Scopus citations

Abstract

Epidermal cells (EC) are a rich source of cytokines that can regulate the function of cells in skin and in other tissues. To organize the array of data pertaining to cytokine expression by EC subpopulations, we have tabulated such data according to cell source, state of cell activation, and type of assay employed. This information forms a background for our own studies, in which reverse transcriptase-polymerase chain reaction (RT-PCR) was used to show that Langerhans cells (LC) are the principal source of mRNA for interleukin 1β and macrophage inflammatory protein-lα (MIP-lα) among unstimulated mouse EC.

Original languageEnglish (US)
Pages (from-to)39-45
Number of pages7
JournalJournal of Investigative Dermatology
Volume99
Issue number5
DOIs
StatePublished - Nov 1992

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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