Cytokine expression by epidermal cell subpopulations

Hiroyuki Matsue, Ponciano D Cruz, Paul R. Bergstresser, Akira Takashima

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Epidermal cells (EC) are a rich source of cytokines that can regulate the function of cells in skin and in other tissues. To organize the array of data pertaining to cytokine expression by EC subpopulations, we have tabulated such data according to cell source, state of cell activation, and type of assay employed. This information forms a background for our own studies, in which reverse transcriptase-polymerase chain reaction (RT-PCR) was used to show that Langerhans cells (LC) are the principal source of mRNA for interleukin 1β and macrophage inflammatory protein-lα (MIP-lα) among unstimulated mouse EC.

Original languageEnglish (US)
Pages (from-to)39-45
Number of pages7
JournalJournal of Investigative Dermatology
Volume99
Issue number5
StatePublished - Nov 1992

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Cytokines
Macrophage Inflammatory Proteins
Polymerase chain reaction
RNA-Directed DNA Polymerase
Interleukin-1
Assays
Skin
Chemical activation
Tissue
Messenger RNA
Langerhans Cells
Reverse Transcriptase Polymerase Chain Reaction

ASJC Scopus subject areas

  • Dermatology

Cite this

Matsue, H., Cruz, P. D., Bergstresser, P. R., & Takashima, A. (1992). Cytokine expression by epidermal cell subpopulations. Journal of Investigative Dermatology, 99(5), 39-45.

Cytokine expression by epidermal cell subpopulations. / Matsue, Hiroyuki; Cruz, Ponciano D; Bergstresser, Paul R.; Takashima, Akira.

In: Journal of Investigative Dermatology, Vol. 99, No. 5, 11.1992, p. 39-45.

Research output: Contribution to journalArticle

Matsue, H, Cruz, PD, Bergstresser, PR & Takashima, A 1992, 'Cytokine expression by epidermal cell subpopulations', Journal of Investigative Dermatology, vol. 99, no. 5, pp. 39-45.
Matsue H, Cruz PD, Bergstresser PR, Takashima A. Cytokine expression by epidermal cell subpopulations. Journal of Investigative Dermatology. 1992 Nov;99(5):39-45.
Matsue, Hiroyuki ; Cruz, Ponciano D ; Bergstresser, Paul R. ; Takashima, Akira. / Cytokine expression by epidermal cell subpopulations. In: Journal of Investigative Dermatology. 1992 ; Vol. 99, No. 5. pp. 39-45.
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