Epidermal cells (EC) are a rich source of cytokines that can regulate the function of cells in skin and in other tissues. To organize the array of data pertaining to cytokine expression by EC subpopulations, we have tabulated such data according to cell source, state of cell activation, and type of assay employed. This information forms a background for our own studies, in which reverse transcriptase-polymerase chain reaction (RT-PCR) was used to show that Langerhans cells (LC) are the principal source of mRNA for interleukin 1β and macrophage inflammatory protein-lα (MIP-lα) among unstimulated mouse EC.
|Original language||English (US)|
|Number of pages||7|
|Journal||Journal of Investigative Dermatology|
|State||Published - Nov 1 1992|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology