Cytomegalovirus Retinitis After Fluocinolone Acetonide (Retisert™) Implant

Rafael L. Ufret-Vincenty, Rishi P. Singh, Careen Y. Lowder, Peter K. Kaiser

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Purpose: To report a case of cytomegalovirus (CMV) retinitis after placement of a fluocinolone acetonide (Retisert™) implant. Design: Interventional case report. Methods: Retrospective chart review. Results: A 65-year-old man with a history of Adamantiades-Behcet disease and bilateral recurrent uveitis that was unresponsive to systemic corticosteroid-sparing immunosuppressive therapy developed clinical evidence of CMV retinitis after receiving his second intravitreal Retisert™ implant in the left eye, while on no systemic immunosuppression. He did not develop CMV retinitis in the right eye despite multiple intraocular and periocular steroid injections. The patient responded well to intravitreal foscarnet followed by placement of an intravitreal ganciclovir implant. Conclusions: Ophthalmologists should be aware of the potential risk for development of CMV retinitis after local ocular immunosuppressive therapy.

Original languageEnglish (US)
Pages (from-to)334-335
Number of pages2
JournalAmerican Journal of Ophthalmology
Volume143
Issue number2
DOIs
StatePublished - Feb 2007

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Fluocinolone Acetonide
Cytomegalovirus Retinitis
Immunosuppressive Agents
Intraocular Injections
Foscarnet
Ganciclovir
Behcet Syndrome
Uveitis
Immunosuppression
Adrenal Cortex Hormones
Steroids
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

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Cytomegalovirus Retinitis After Fluocinolone Acetonide (Retisert™) Implant. / Ufret-Vincenty, Rafael L.; Singh, Rishi P.; Lowder, Careen Y.; Kaiser, Peter K.

In: American Journal of Ophthalmology, Vol. 143, No. 2, 02.2007, p. 334-335.

Research output: Contribution to journalArticle

Ufret-Vincenty, Rafael L. ; Singh, Rishi P. ; Lowder, Careen Y. ; Kaiser, Peter K. / Cytomegalovirus Retinitis After Fluocinolone Acetonide (Retisert™) Implant. In: American Journal of Ophthalmology. 2007 ; Vol. 143, No. 2. pp. 334-335.
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