Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3

Agriculture & Biology

• cysteine proteinases 89%
• cell death 72%
• T-lymphocytes 70%
• proteinases 58%
• aspartic acid 49%
• apoptosis 47%
• graft rejection 37%
• cytotoxic T-lymphocytes 36%
• autoimmune diseases 35%
• zymogens 33%
• natural killer cells 32%
• Caenorhabditis elegans 27%
• pathogenesis 23%
• cytotoxicity 22%
• granules 21%
• lymphocytes 21%
• neoplasms 19%
• viruses 16%
• cells 16%
• monitoring 16%
• enzymes 11%
• genes 8%

Medicine & Life Sciences

• Granzymes 100%
• Caspase 1 95%
• T-Lymphocytes 47%
• Cysteine Proteases 47%
• Perforin 33%
• Cell Death 29%
• Aspartic Acid 26%
• perforin-granzyme B 19%
• Enzyme Precursors 16%
• Apoptosis 15%
• Jurkat Cells 15%
• Caenorhabditis elegans 14%
• Graft Rejection 14%
• Cytotoxic T-Lymphocytes 13%
• Natural Killer Cells 11%
• Caspase 3 11%
• Autoimmune Diseases 11%
• Acquired Immunodeficiency Syndrome 10%
• Lymphocytes 8%
• Viruses 8%
• Enzymes 7%
• Genes 5%
• Neoplasms 4%

Chemical Compounds

• Apoptotic 89%
• Effector 84%
• Cell Death 82%
• Aspartate Residue 74%
• Cysteine 66%
• Cleavage 17%