Abstract
This data article provided additional data related to the research article entitled “Brain structural abnormalities in emotional regulation and sensory processing regions associated with anxious depression” Peng et al.,2019. Correlation analyses were conducted for clinical information (HAMD total, anxiety/somatization scores, HAMA total and illness duration) and identified regional gray matter volumes in all patients with anxious depression and non-anxious depression. More detailed correlation analysis was applied for each item of anxiety factor and reginal gray matter volumes to find which items were more associated with structural alterations in patients. Data showed that mean values of regional gray matter volumes in left postcentral gyrus (PCG) were positively associated with HAMD total and anxiety factor scores in anxious depression group. More detailed correlation analysis considering each item of anxiety factor revealed that, item 10 (psychic anxiety) and Item15 (hypochondriasis) were most significantly and positively associated with regional gray matter volumes in left PCG in anxious group. While HAMA scores and illness duration showed no significant correlation with any regional gray matter volume in both patient groups. Sample size matched groups were selected to explore possible replicability of imaging results. It revealed that different gray matter volumes in right inferior frontal gyrus were most robust findings among three groups. And anxious group had larger gray matter volumes in left PCG than non-anxious depression, despite of not survived after multiple comparisons corrections.
| Original language | English (US) |
|---|---|
| Article number | 104322 |
| Journal | Data in Brief |
| Volume | 25 |
| DOIs | |
| State | Published - Aug 1 2019 |
| Externally published | Yes |
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Keywords
- Anxious depression
- Gray matter
- Non-anxious depression
ASJC Scopus subject areas
- General
Cite this
Data on gray matter alterations in anxious depression. / Peng, Wei; Jia, Zhiyun; Huang, Xiaoqi; Lui, Su; Kuang, Weihong; Sweeney, John A.; Gong, Qiyong.
In: Data in Brief, Vol. 25, 104322, 01.08.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Data on gray matter alterations in anxious depression
AU - Peng, Wei
AU - Jia, Zhiyun
AU - Huang, Xiaoqi
AU - Lui, Su
AU - Kuang, Weihong
AU - Sweeney, John A.
AU - Gong, Qiyong
PY - 2019/8/1
Y1 - 2019/8/1
N2 - This data article provided additional data related to the research article entitled “Brain structural abnormalities in emotional regulation and sensory processing regions associated with anxious depression” Peng et al.,2019. Correlation analyses were conducted for clinical information (HAMD total, anxiety/somatization scores, HAMA total and illness duration) and identified regional gray matter volumes in all patients with anxious depression and non-anxious depression. More detailed correlation analysis was applied for each item of anxiety factor and reginal gray matter volumes to find which items were more associated with structural alterations in patients. Data showed that mean values of regional gray matter volumes in left postcentral gyrus (PCG) were positively associated with HAMD total and anxiety factor scores in anxious depression group. More detailed correlation analysis considering each item of anxiety factor revealed that, item 10 (psychic anxiety) and Item15 (hypochondriasis) were most significantly and positively associated with regional gray matter volumes in left PCG in anxious group. While HAMA scores and illness duration showed no significant correlation with any regional gray matter volume in both patient groups. Sample size matched groups were selected to explore possible replicability of imaging results. It revealed that different gray matter volumes in right inferior frontal gyrus were most robust findings among three groups. And anxious group had larger gray matter volumes in left PCG than non-anxious depression, despite of not survived after multiple comparisons corrections.
AB - This data article provided additional data related to the research article entitled “Brain structural abnormalities in emotional regulation and sensory processing regions associated with anxious depression” Peng et al.,2019. Correlation analyses were conducted for clinical information (HAMD total, anxiety/somatization scores, HAMA total and illness duration) and identified regional gray matter volumes in all patients with anxious depression and non-anxious depression. More detailed correlation analysis was applied for each item of anxiety factor and reginal gray matter volumes to find which items were more associated with structural alterations in patients. Data showed that mean values of regional gray matter volumes in left postcentral gyrus (PCG) were positively associated with HAMD total and anxiety factor scores in anxious depression group. More detailed correlation analysis considering each item of anxiety factor revealed that, item 10 (psychic anxiety) and Item15 (hypochondriasis) were most significantly and positively associated with regional gray matter volumes in left PCG in anxious group. While HAMA scores and illness duration showed no significant correlation with any regional gray matter volume in both patient groups. Sample size matched groups were selected to explore possible replicability of imaging results. It revealed that different gray matter volumes in right inferior frontal gyrus were most robust findings among three groups. And anxious group had larger gray matter volumes in left PCG than non-anxious depression, despite of not survived after multiple comparisons corrections.
KW - Anxious depression
KW - Gray matter
KW - Non-anxious depression
UR - http://www.scopus.com/inward/record.url?scp=85070375617&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070375617&partnerID=8YFLogxK
U2 - 10.1016/j.dib.2019.104322
DO - 10.1016/j.dib.2019.104322
M3 - Article
C2 - 31453297
AN - SCOPUS:85070375617
VL - 25
JO - Data in Brief
JF - Data in Brief
SN - 2352-3409
M1 - 104322
ER -