Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression

S. Susan Hedayati, Hayden B. Bosworth, Libbie P. Briley, Richard J. Sloane, Carl F. Pieper, Paul L. Kimmel, Lynda A. Szczech

Research output: Contribution to journalArticle

179 Citations (Scopus)

Abstract

Depressive symptoms, assessed using a self-report type of questionnaire, have been associated with poor outcomes in dialysis patients. Here we determined if depressive disorders diagnosed by physicians are also associated with such outcomes. Ninety-eight consecutive patients on chronic hemodialysis underwent the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders administered by a physician. Depression was diagnosed in about a quarter of the patients. Associations adjusted for age, gender, race, time on dialysis and co-morbidity were determined using survival analysis. Using time to event (death or hospitalization) models of analysis the hazard ratios were 2.11 and 2.07 in unadjusted and adjusted models respectively. The finding of poor outcome using a formal structured physician interview suggests that a prospective study is needed to determine whether treatment of depression affects clinical outcomes.

Original languageEnglish (US)
Pages (from-to)930-936
Number of pages7
JournalKidney International
Volume74
Issue number7
DOIs
StatePublished - Oct 2008

Fingerprint

Renal Dialysis
Hospitalization
Depression
Physicians
Dialysis
Interviews
Survival Analysis
Depressive Disorder
Proportional Hazards Models
Diagnostic and Statistical Manual of Mental Disorders
Self Report
Prospective Studies
Morbidity
Therapeutics
Surveys and Questionnaires

Keywords

  • Depression
  • Dialysis
  • Hospitalization
  • Mortality

ASJC Scopus subject areas

  • Nephrology

Cite this

Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression. / Hedayati, S. Susan; Bosworth, Hayden B.; Briley, Libbie P.; Sloane, Richard J.; Pieper, Carl F.; Kimmel, Paul L.; Szczech, Lynda A.

In: Kidney International, Vol. 74, No. 7, 10.2008, p. 930-936.

Research output: Contribution to journalArticle

Hedayati, S. Susan ; Bosworth, Hayden B. ; Briley, Libbie P. ; Sloane, Richard J. ; Pieper, Carl F. ; Kimmel, Paul L. ; Szczech, Lynda A. / Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression. In: Kidney International. 2008 ; Vol. 74, No. 7. pp. 930-936.
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