Decoding Dopamine Signaling

James A. Bibb

doi:10.1016/j.cell.2005.07.011

Decoding Dopamine Signaling

James A. Bibb

Research output: Contribution to journal › Short survey › peer-review

47 Scopus citations

Abstract

Dopamine is a key neurotransmitter that is important for many physiological functions including motor control, mood, and the reward pathway. In this issue of Cell, the laboratories of Marc Caron and Li-Huei Tsai identify two very different molecules - β-arrestin 2 and Par-4, respectively - that unexpectedly are involved in dopamine signaling via the D2 receptor. These two new signaling pathways mediate the actions of dopamine on behavior and facilitate crosstalk between different signaling pathways that are activated by binding of dopamine to the D2 receptor.

Original language	English (US)
Pages (from-to)	153-155
Number of pages	3
Journal	Cell
Volume	122
Issue number	2
DOIs	https://doi.org/10.1016/j.cell.2005.07.011
State	Published - Jul 29 2005

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2005.07.011

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title = "Decoding Dopamine Signaling",

abstract = "Dopamine is a key neurotransmitter that is important for many physiological functions including motor control, mood, and the reward pathway. In this issue of Cell, the laboratories of Marc Caron and Li-Huei Tsai identify two very different molecules - β-arrestin 2 and Par-4, respectively - that unexpectedly are involved in dopamine signaling via the D2 receptor. These two new signaling pathways mediate the actions of dopamine on behavior and facilitate crosstalk between different signaling pathways that are activated by binding of dopamine to the D2 receptor.",

author = "Bibb, {James A.}",

note = "Funding Information: I thank J.P. Albanesi, D.C. Cooper, and K.A. Neve for helpful comments. J.A.B. is supported by the National Institute of Drug Abuse and the Ella McFadden Charitable Trust Fund at the Southwestern Medical Foundation.",

year = "2005",

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doi = "10.1016/j.cell.2005.07.011",

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journal = "Cell",

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T1 - Decoding Dopamine Signaling

AU - Bibb, James A.

N1 - Funding Information: I thank J.P. Albanesi, D.C. Cooper, and K.A. Neve for helpful comments. J.A.B. is supported by the National Institute of Drug Abuse and the Ella McFadden Charitable Trust Fund at the Southwestern Medical Foundation.

PY - 2005/7/29

Y1 - 2005/7/29

N2 - Dopamine is a key neurotransmitter that is important for many physiological functions including motor control, mood, and the reward pathway. In this issue of Cell, the laboratories of Marc Caron and Li-Huei Tsai identify two very different molecules - β-arrestin 2 and Par-4, respectively - that unexpectedly are involved in dopamine signaling via the D2 receptor. These two new signaling pathways mediate the actions of dopamine on behavior and facilitate crosstalk between different signaling pathways that are activated by binding of dopamine to the D2 receptor.

AB - Dopamine is a key neurotransmitter that is important for many physiological functions including motor control, mood, and the reward pathway. In this issue of Cell, the laboratories of Marc Caron and Li-Huei Tsai identify two very different molecules - β-arrestin 2 and Par-4, respectively - that unexpectedly are involved in dopamine signaling via the D2 receptor. These two new signaling pathways mediate the actions of dopamine on behavior and facilitate crosstalk between different signaling pathways that are activated by binding of dopamine to the D2 receptor.

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U2 - 10.1016/j.cell.2005.07.011

DO - 10.1016/j.cell.2005.07.011

M3 - Short survey

C2 - 16051141

AN - SCOPUS:22744439314

SN - 0092-8674

VL - 122

SP - 153

EP - 155

JO - Cell

JF - Cell

IS - 2

ER -

Decoding Dopamine Signaling

Abstract

ASJC Scopus subject areas

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