Abstract
The LDL receptor plays a central role in the control of plasma cholesterol levels and the prevention of coronary artery disease. Recent studies now shed light on the structural organization of several independently folded modules and domains from which the receptor is assembled, providing substantial insights into the mechanics of receptor function and the consequences of disease causing mutations.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 476-478 |
| Number of pages | 3 |
| Journal | Nature Structural Biology |
| Volume | 8 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2001 |
ASJC Scopus subject areas
- Structural Biology
- Biochemistry
- Genetics