Deconstructing the LDL receptor - A rhapsody in pieces

Research output: Contribution to journalShort survey

15 Scopus citations


The LDL receptor plays a central role in the control of plasma cholesterol levels and the prevention of coronary artery disease. Recent studies now shed light on the structural organization of several independently folded modules and domains from which the receptor is assembled, providing substantial insights into the mechanics of receptor function and the consequences of disease causing mutations.

Original languageEnglish (US)
Pages (from-to)476-478
Number of pages3
JournalNature Structural Biology
Issue number6
StatePublished - Jun 21 2001


ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry
  • Genetics

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