Deep brain stimulation for dystonia

Jessika Suescun, Erin Furr-Stimming, Neepa Patel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Dystonia is a heterogeneous movement disorder characterized by sustained or intermittent contraction of agonist and antagonist muscles producing abnormal postures. Dystonia can be focal, multifocal, segmental or generalized. Botulinum toxin injections are generally effective in treating focal dystonia. Oral medications can be effective in attenuating generalized and segmental dystonia, but have limitations. Generalized dystonia, however, is more often refractory to available medical therapies. Deep brain stimulation (DBS) has been established as an effective intervention to treat patients with dystonia refractory to medical therapy. This chapter describes the current accepted classification scheme for diagnosing dystonia, specific considerations for the phenomenology, etiology and treatment, and reviews the current literature evidence supporting the use of DBS in a variety of dystonia syndromes; it also provides general consideration for patient selection and recommendations for approach to programming DBS for the treatment of dystonia.

Original languageEnglish (US)
Title of host publicationDeep Brain Stimulation
PublisherNova Science Publishers, Inc.
Pages169-194
Number of pages26
ISBN (Print)9781634832878, 9781634832823
StatePublished - Jul 1 2015

ASJC Scopus subject areas

  • Neuroscience(all)

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    Suescun, J., Furr-Stimming, E., & Patel, N. (2015). Deep brain stimulation for dystonia. In Deep Brain Stimulation (pp. 169-194). Nova Science Publishers, Inc..