Deep Brain Stimulation for Tourette Syndrome

Research output: Contribution to journalReview articlepeer-review

Abstract

Gilles de la Tourette syndrome is a movement disorder characterized by repetitive stereotyped motor and phonic movements with varying degrees of psychiatric comorbidity. Deep brain stimulation (DBS) has emerged as a novel therapeutic intervention for patients with refractory Tourette syndrome. Since 1999, more than 100 patients have undergone DBS at various targets within the corticostriatothalamocortical network thought to be implicated in the underlying pathophysiology of Tourette syndrome. Future multicenter clinical trials and the use of a centralized online database to compare the results are necessary to determine the efficacy of DBS for Tourette syndrome.

Original languageEnglish (US)
Pages (from-to)117-135
Number of pages19
JournalNeurosurgery clinics of North America
Volume25
Issue number1
DOIs
StatePublished - Jan 2014
Externally publishedYes

Keywords

  • Deep brain stimulation
  • Neuromodulation
  • Tics
  • Tourette Syndrome

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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