Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus

Kenneth Devault, Barry P. Mcmahon, Altay Celebi, Guido Costamagna, Michele Marchese, John O. Clarke, Reza A. Hejazi, Richard W. Mccallum, Vincenzo Savarino, Patrizia Zentilin, Edoardo Savarino, Mike Thomson, Rhonda F. Souza, Claire L. Donohoe, Naoimh J. O'Farrell, John V. Reynolds

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

The following paper on gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) includes commentaries on defining esophageal landmarks; new techniques for evaluating upper esophageal sphincter (UES) tone; differential diagnosis of GERD, BE, and hiatal hernia (HH); the use of high-resolution manometry for evaluation of reflux; the role of fundic relaxation in reflux; the use of 24-h esophageal pH-impedance testing in differentiating acid from nonacid reflux and its potential inclusion in future Rome criteria; classification of endoscopic findings in GERD; the search for the cell origin that generates BE; and the relationship between BE, Barrett's carcinoma, and obesity.

Original languageEnglish (US)
Pages (from-to)278-295
Number of pages18
JournalAnnals of the New York Academy of Sciences
Volume1300
Issue number1
DOIs
StatePublished - Oct 2013

Keywords

  • Dysphagia
  • Endoscopy
  • GERD
  • Manometry
  • NERD

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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    Devault, K., Mcmahon, B. P., Celebi, A., Costamagna, G., Marchese, M., Clarke, J. O., Hejazi, R. A., Mccallum, R. W., Savarino, V., Zentilin, P., Savarino, E., Thomson, M., Souza, R. F., Donohoe, C. L., O'Farrell, N. J., & Reynolds, J. V. (2013). Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus. Annals of the New York Academy of Sciences, 1300(1), 278-295. https://doi.org/10.1111/nyas.12253