Defining the biochemistry of mismatch repair

Research output: Contribution to journalArticle

Abstract

Following a period of intensive and illuminating genetic analysis, the biochemical mechanism of mismatch repair was deciphered by Paul Modrich and his colleagues. The establishment of an in vitro assay that specifically supports strand-specific excision repair of mismatched bases was a seminal contribution to this body of work.

Original languageEnglish (US)
Pages (from-to)133-139
Number of pages7
JournalDNA repair
Volume4
Issue number1
DOIs
StatePublished - Jan 2 2005

Keywords

  • Biochemistry
  • Mismatch repair
  • Restriction endonucleases

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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