Defining uterine tachysystole: How much is too much?

Robert D. Stewart, April T. Bleich, Julie Y. Lo, James M. Alexander, Donald D. McIntire, Kenneth J. Leveno

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Objective: We sought to determine if uterine tachysystole, <6 contractions per 10 minutes, within the first 4 hours of labor induction, is associated with adverse infant outcomes. Study Design: This was a prospective cohort study of 584 women <37 weeks' gestation undergoing induction of labor with 100 μg of oral misoprostol. Fetal heart rate tracings were analyzed for contractions per 10 minutes during the initial 4 hours after misoprostol administration. Patients were analyzed based on the maximum number of contractions per 10 minutes. Infant condition at birth was assessed using the fetal vulnerability composite. Results: Adverse infant outcomes showed no association with increasing number of contractions per 10 minutes. Six or more contractions in 10 minutes were significantly associated with fetal heart rate decelerations (P ≤.001). Analysis was performed using the maximum number of contractions per 30 minutes with similar results. Conclusion: Uterine tachysystole, as currently defined, when occurring remote from delivery is not associated with adverse infant outcomes.

Original languageEnglish (US)
Pages (from-to)290.e1-290.e6
JournalAmerican journal of obstetrics and gynecology
Volume207
Issue number4
DOIs
StatePublished - Oct 2012

Keywords

  • abnormal labor
  • misoprostol
  • uterine hyperstimulation
  • uterine tachysystole

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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