Delayed enhancement of the intraventricular septum following an extraordinary endurance exercise

Paul S. Bhella, Jacob P. Kelly, Ronald M Peshock, Benjamin D Levine

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Cardiac fatigue and elevations in cardiac biomarkers have been described following prolonged exertion in endurance athletes. We comprehensively evaluated a highly trained 46-year-old man attempting a North American transcontinental run in a record time of 45 consecutive days. After running 1460 km and ascending over 2600 m, the run was ended prematurely on day 17 following a leg injury; in support of the event, the subject cycled an additional 1580 km. Echocardiography and biomarker analysis performed pre-event and while running revealed no decrement in systolic function and undetectable levels of troponin I and T. Post-event cardiac MRI demonstrated the interval appearance of delayed enhancement of gadolinium at the inferior insertion of the right ventricle and in the interventricular septum - a novel finding that may represent subtle inflammation secondary to a combined exercise and altitude effect.

Original languageEnglish (US)
JournalBMJ Case Reports
DOIs
StatePublished - Dec 2 2010

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Running
Leg Injuries
Biomarkers
Exercise
Troponin T
Troponin I
Gadolinium
Athletes
Heart Ventricles
Fatigue
Echocardiography
Inflammation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Delayed enhancement of the intraventricular septum following an extraordinary endurance exercise. / Bhella, Paul S.; Kelly, Jacob P.; Peshock, Ronald M; Levine, Benjamin D.

In: BMJ Case Reports, 02.12.2010.

Research output: Contribution to journalArticle

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