@inbook{48507f94867641e389b0b5bcea07716b,
title = "Delivery of the porcupine inhibitor WNT974 in mice",
abstract = "We describe here a technique for delivering the porcupine inhibitor WNT974 (formerly LGK974) in mice. The protocol entails once-a-day oral delivery of WNT974 for up to 3 months at a concentration sufficient to achieve systemic Wnt pathway inhibition with limited toxicity as measured by weight change. This route of delivery enables extended durations of Wnt signaling inhibition in a mammalian model organism.",
keywords = "Drug delivery, Mice, Porcupine, Wnt974/LGK974",
author = "Zhang, {Li Shu} and Lawrence Lum",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2016.",
year = "2016",
doi = "10.1007/978-1-4939-6393-5_12",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "111--117",
booktitle = "Methods in Molecular Biology",
}