Denitrogenative Transformations of Pyridotriazoles and Related Compounds: Synthesis of N-Containing Heterocyclic Compounds and beyond

Dongari Yadagiri, Mónica Rivas, Vladimir Gevorgyan

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

The high demand for new and efficient routes toward synthesis of nitrogen-containing heterocyclic scaffolds has inspired organic chemists to discover several methodologies over recent years. This Perspective highlights one standout approach, which involves the use of pyridotriazoles and related compounds in denitrogenative transformations. Readily available pyridotriazoles undergo ring-chain isomerization to produce uniquely reactive α-diazoimines. Such reactivity, enabled by metal catalysts, additives, or visible-light irradiation, can be applied in transannulation, insertion, cyclopropanation, and many other transformations.

Original languageEnglish (US)
Pages (from-to)11030-11046
Number of pages17
JournalJournal of Organic Chemistry
Volume85
Issue number17
DOIs
StatePublished - Sep 4 2020
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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