Depression and anxiety in Singaporean high-risk pregnancies - prevalence and screening

Pavaani Thiagayson, Gita Krishnaswamy, May Li Lim, Sharon Cohan Sung, Charlotte Louise Haley, Daniel Shuen Sheng Fung, John Carson Allen, Helen Chen

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Objective: Data on psychiatric morbidity in high-risk pregnant Singaporean women are limited. This study aimed to establish the prevalence of antenatal depression and anxiety in high-risk pregnancies, compare the prevalence of antenatal depression in high-risk pregnancies vs. pregnancies of unspecified obstetric risk and examine the Edinburgh Postnatal Depression Scale (EPDS) and State Trait Anxiety Inventory (STAI) as screening tools for these disorders. Method: Two hundred high-risk pregnant inpatients at a national public maternity hospital were included. Three psychometric assessment tools were used to evaluate all participants: the diagnostic Mini International Neuropsychiatric Interview and the screening EPDS and STAI. Results: Rates of major depression, minor depression, anxiety disorder (agoraphobia, generalized anxiety disorder, panic disorder), and comorbid depression and anxiety were 11%, 7%, 12.5% and 5%, respectively. Major depression was more prevalent in high-risk pregnancies than in the historical cohort of unspecified obstetric risk (11% versus 4.3%). EPDS (cutoff 8/9) screens well for depression and anxiety in high-risk pregnancies (area under the receiver operating characteristic curve=0.82-0.87). Conclusion: Antenatal depression and anxiety are highly prevalent in a sample of high-risk pregnant Singaporean women. EPDS performs well in screening for depression and anxiety in high-risk pregnant women, with further psychiatric assessment recommended for women with score ≥ 9.

Original languageEnglish (US)
Pages (from-to)112-116
Number of pages5
JournalGeneral Hospital Psychiatry
Volume35
Issue number2
DOIs
StatePublished - Mar 1 2013

Keywords

  • Anxiety
  • Depression
  • High-risk pregnancies
  • Prevalence
  • Screening

ASJC Scopus subject areas

  • Psychiatry and Mental health

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