Depression and dexamethasone suppression testing in children and adolescents

G. J. Emslie, W. A. Weinberg, A. J. Rush, J. Weissenburger, L. Parkin-Feigenbaum

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The authors compare the incidence of dexamethasone nonsuppression in a large group of child and adolescent inpatients (N = 94) diagnosed by two criteria (DSM-III and Weinberg criteria). The incidence of dexamethasone suppression test nonsuppression in patients diagnosed with DSM-III major depressive disorder (n = 33) was 55%, compared to 11% in those with no affective disorder (n = 35). This was compared to the incidence of dexamethasone suppression test nonsuppression utilizing Weinberg criteria. In addition, symptoms that to varying degrees discriminated suppressors from nonsuppressors were examined. These included change in school performance and, to a lesser degree, somatic complaints and weight and appetite changes. Differences in the diagnostic criteria are discussed.

Original languageEnglish (US)
Pages (from-to)31-37
Number of pages7
JournalJournal of Child Neurology
Volume2
Issue number1
StatePublished - 1987

Fingerprint

Dexamethasone
Depression
Diagnostic and Statistical Manual of Mental Disorders
Incidence
Major Depressive Disorder
Appetite
Mood Disorders
Inpatients
Weights and Measures

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

Cite this

Emslie, G. J., Weinberg, W. A., Rush, A. J., Weissenburger, J., & Parkin-Feigenbaum, L. (1987). Depression and dexamethasone suppression testing in children and adolescents. Journal of Child Neurology, 2(1), 31-37.

Depression and dexamethasone suppression testing in children and adolescents. / Emslie, G. J.; Weinberg, W. A.; Rush, A. J.; Weissenburger, J.; Parkin-Feigenbaum, L.

In: Journal of Child Neurology, Vol. 2, No. 1, 1987, p. 31-37.

Research output: Contribution to journalArticle

Emslie, GJ, Weinberg, WA, Rush, AJ, Weissenburger, J & Parkin-Feigenbaum, L 1987, 'Depression and dexamethasone suppression testing in children and adolescents', Journal of Child Neurology, vol. 2, no. 1, pp. 31-37.
Emslie GJ, Weinberg WA, Rush AJ, Weissenburger J, Parkin-Feigenbaum L. Depression and dexamethasone suppression testing in children and adolescents. Journal of Child Neurology. 1987;2(1):31-37.
Emslie, G. J. ; Weinberg, W. A. ; Rush, A. J. ; Weissenburger, J. ; Parkin-Feigenbaum, L. / Depression and dexamethasone suppression testing in children and adolescents. In: Journal of Child Neurology. 1987 ; Vol. 2, No. 1. pp. 31-37.
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