TY - JOUR
T1 - Dermal, subcutaneous, and tendon xanthomas
T2 - Diagnostic markers for specific lipoprotein disorders
AU - Cruz, Ponciano D
AU - East, C.
AU - Bergstresser, P. R.
N1 - Funding Information:
Financial support for color reproduction was received from Ortho Pharmaceutical Corporation, Raritan, NJ.
PY - 1988
Y1 - 1988
N2 - Many patients with lipoprotein disorders are at increased risk for the development of premature atherosclerosis and, less commonly, other disorders that cause systemic morbidity. In some of these patients, xanthomas also develop and provide cutaneous markers for the lipoprotein disorder. As advances in molecular biology refine our understanding of lipoprotein metabolism, it has become increasingly clear that several types of xanthomas are associated with specific disease states. This article presents a differential diagnosis of xanthomas that incorporates contemporary thinking about lipoprotein disorders and focuses on the relationship between abnormalities in lipoprotein metabolism, content, or structure and the development of specific xanthomas.
AB - Many patients with lipoprotein disorders are at increased risk for the development of premature atherosclerosis and, less commonly, other disorders that cause systemic morbidity. In some of these patients, xanthomas also develop and provide cutaneous markers for the lipoprotein disorder. As advances in molecular biology refine our understanding of lipoprotein metabolism, it has become increasingly clear that several types of xanthomas are associated with specific disease states. This article presents a differential diagnosis of xanthomas that incorporates contemporary thinking about lipoprotein disorders and focuses on the relationship between abnormalities in lipoprotein metabolism, content, or structure and the development of specific xanthomas.
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U2 - 10.1016/S0190-9622(88)70157-7
DO - 10.1016/S0190-9622(88)70157-7
M3 - Review article
C2 - 3042820
AN - SCOPUS:0023787740
SN - 0190-9622
VL - 19
SP - 95
EP - 111
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 1
ER -