Dermal, subcutaneous, and tendon xanthomas: Diagnostic markers for specific lipoprotein disorders

Ponciano D Cruz, C. East, P. R. Bergstresser

Research output: Contribution to journalReview article

69 Scopus citations

Abstract

Many patients with lipoprotein disorders are at increased risk for the development of premature atherosclerosis and, less commonly, other disorders that cause systemic morbidity. In some of these patients, xanthomas also develop and provide cutaneous markers for the lipoprotein disorder. As advances in molecular biology refine our understanding of lipoprotein metabolism, it has become increasingly clear that several types of xanthomas are associated with specific disease states. This article presents a differential diagnosis of xanthomas that incorporates contemporary thinking about lipoprotein disorders and focuses on the relationship between abnormalities in lipoprotein metabolism, content, or structure and the development of specific xanthomas.

Original languageEnglish (US)
Pages (from-to)95-111
Number of pages17
JournalJournal of the American Academy of Dermatology
Volume19
Issue number1
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Dermatology

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