Design and development of novel and practical PET detectors for advanced imaging applications

Xishan Sun, Kai Lou, Zhi Deng, Joseph G. Meier, Yiping Shao

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

New DOI-measurable PET detectors have been designed, developed and evaluated with advanced silicon photomultiplier (SiPM) and readout technologies. The detector consists of an 8×8 array of 1.5×1.5×20 or 1.5×1.5×30 mm3 LYSO scintillators which is optically coupled to a 4×4 array of 3×3 mm2 SiPM array at each crystal array end through a 2 mm thick optical plate. Scintillator surfaces, reflectors and coupling were designed and fabricated to reserve the air-gap to achieve high depth-of-interaction (DOI) resolution and other detection performance. The insensitive edges around each detector is less than 0.2 mm, making it practical to seamlessly tile detectors together to assemble a large size detector panel for developing a PET system. A 16-ch ASIC based PCB readout electronics was developed to solve the challenging SiPM array readout problem. Each compact PCB contains 4 ASIC chips and one detector-level FPGA, with analog signal being inputted from each SiPM array through a flexible printed circuit cable, converted to digital timing pulses, processed online by FPGA to record interaction information (energy, timing, and position), and transferred through a fast LVDS connection to system FPGA for event selection and data acquisition. Initial measurements showed excellent crystal identification with all crystals were clearly separated from each other in a flood source image, with resolutions of energy, timing and DOI were around 17%, 2.7 ns and 2.0 mm (mean value), respectively. Overall, comparing to the previous prototype DOI detectors we developed, the new detector is simplified in design without using complicated light guide yet with significantly improved DOI resolution (from ∼5 to ∼2 mm), more compact packaging for making a large size flat-panel detector, and more integrated and fast readout electronics. The new detector and readout is expected leading to an advanced PET with leapfrog imaging performance improvement.

Original languageEnglish (US)
Title of host publication2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479960972
DOIs
Publication statusPublished - Mar 10 2016
EventIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014 - Seattle, United States
Duration: Nov 8 2014Nov 15 2014

Other

OtherIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
CountryUnited States
CitySeattle
Period11/8/1411/15/14

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ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

Cite this

Sun, X., Lou, K., Deng, Z., Meier, J. G., & Shao, Y. (2016). Design and development of novel and practical PET detectors for advanced imaging applications. In 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014 [7430969] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2014.7430969