Design and evaluation of a bacterial clinical infectious diseases ontology.

Claire L. Gordon, Stephanie Pouch, Lindsay G. Cowell, Mary Regina Boland, Heather L. Platt, Albert Goldfain, Chunhua Weng

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

With antimicrobial resistance increasing worldwide, there is a great need to use automated antimicrobial decision support systems (ADSSs) to lower antimicrobial resistance rates by promoting appropriate antimicrobial use. However, they are infrequently used mostly because of their poor interoperability with different health information technologies. Ontologies can augment portable ADSSs by providing an explicit knowledge representation for biomedical entities and their relationships, helping to standardize and integrate heterogeneous data resources. We developed a bacterial clinical infectious diseases ontology (BCIDO) using Protégé-OWL. BCIDO defines a controlled terminology for clinical infectious diseases along with domain knowledge commonly used in hospital settings for clinical infectious disease treatment decision-making. BCIDO has 599 classes and 2355 object properties. Terms were imported from or mapped to Systematized Nomenclature of Medicine, Unified Medical Language System, RxNorm and National Center for Bitechnology Information Organismal Classification where possible. Domain expert evaluation using the "laddering" technique, ontology visualization, and clinical notes and scenarios, confirmed the correctness and potential usefulness of BCIDO.

Original languageEnglish (US)
Pages (from-to)502-511
Number of pages10
JournalAMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
Volume2013
StatePublished - 2013

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Communicable Diseases
RxNorm
Systematized Nomenclature of Medicine
Unified Medical Language System
Information Centers
Medical Informatics
Terminology
Decision Making

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Design and evaluation of a bacterial clinical infectious diseases ontology. / Gordon, Claire L.; Pouch, Stephanie; Cowell, Lindsay G.; Boland, Mary Regina; Platt, Heather L.; Goldfain, Albert; Weng, Chunhua.

In: AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium, Vol. 2013, 2013, p. 502-511.

Research output: Contribution to journalArticle

Gordon, Claire L. ; Pouch, Stephanie ; Cowell, Lindsay G. ; Boland, Mary Regina ; Platt, Heather L. ; Goldfain, Albert ; Weng, Chunhua. / Design and evaluation of a bacterial clinical infectious diseases ontology. In: AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2013 ; Vol. 2013. pp. 502-511.
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