Design and fabrication of phantoms using stereolithography for small-animal imaging systems

Mi Ae Park, Robert E. Zimmerman, Andrew Taberner, Michael W. Kaye, Stephen C. Moore

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Purpose: We have investigated a new technology for fabricating phantoms with fine details for use in small-animal imaging. Procedures: We used a high-resolution, 3-D stereolithography (SL) system to produce performance-evaluation phantoms such as cold-rod Derenzo, hot-channel Derenzo, and Defrise phantoms. SL performance was estimated by measuring the dimensions of many structures using a microscope. We also evaluated the degree of water absorption by two different SL resins, Somos® 11120 and Accura® 40, after curing. Results: The average bias and precision of the cold-rod structures over the size range 0.5 to 1.0 mm, were -0.4% and 1.74%, respectively. The water absorption study showed that Somos® 11120 is a more suitable material for nuclear medicine applications. Conclusion: We have demonstrated that SL is a robust and accurate method for fabrication of phantoms for small-animal imaging systems.

Original languageEnglish (US)
Pages (from-to)231-236
Number of pages6
JournalMolecular Imaging and Biology
Volume10
Issue number5
DOIs
StatePublished - 2008
Externally publishedYes

Keywords

  • MicroCT
  • MicroMRI
  • MicroPET
  • MicroSPECT
  • Molecular imaging
  • Phantom
  • Quality control
  • Small-animal imaging
  • Stereolithography

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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