Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART)

Henry E. Wang, David K. Prince, Shannon W. Stephens, Heather Herren, Mohamud Daya, Neal Richmond, Jestin Carlson, Craig Warden, M. Riccardo Colella, Ashley Brienza, Tom P. Aufderheide, Ahamed H. Idris, Robert Schmicker, Susanne May, Graham Nichol

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Airway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.

Original languageEnglish (US)
Pages (from-to)57-64
Number of pages8
JournalResuscitation
Volume101
DOIs
StatePublished - Apr 1 2016

Fingerprint

Airway Management
Resuscitation
Out-of-Hospital Cardiac Arrest
Intratracheal Intubation
Emergency Medical Services
Masks
Cross-Over Studies

Keywords

  • Airway management
  • Cardiopulmonary arrest
  • Clinical trials
  • Emergency medical services
  • Intubation (intratracheal)
  • Resuscitation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Emergency
  • Emergency Medicine

Cite this

Wang, H. E., Prince, D. K., Stephens, S. W., Herren, H., Daya, M., Richmond, N., ... Nichol, G. (2016). Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART). Resuscitation, 101, 57-64. https://doi.org/10.1016/j.resuscitation.2016.01.012

Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART). / Wang, Henry E.; Prince, David K.; Stephens, Shannon W.; Herren, Heather; Daya, Mohamud; Richmond, Neal; Carlson, Jestin; Warden, Craig; Colella, M. Riccardo; Brienza, Ashley; Aufderheide, Tom P.; Idris, Ahamed H.; Schmicker, Robert; May, Susanne; Nichol, Graham.

In: Resuscitation, Vol. 101, 01.04.2016, p. 57-64.

Research output: Contribution to journalArticle

Wang, HE, Prince, DK, Stephens, SW, Herren, H, Daya, M, Richmond, N, Carlson, J, Warden, C, Colella, MR, Brienza, A, Aufderheide, TP, Idris, AH, Schmicker, R, May, S & Nichol, G 2016, 'Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART)', Resuscitation, vol. 101, pp. 57-64. https://doi.org/10.1016/j.resuscitation.2016.01.012
Wang, Henry E. ; Prince, David K. ; Stephens, Shannon W. ; Herren, Heather ; Daya, Mohamud ; Richmond, Neal ; Carlson, Jestin ; Warden, Craig ; Colella, M. Riccardo ; Brienza, Ashley ; Aufderheide, Tom P. ; Idris, Ahamed H. ; Schmicker, Robert ; May, Susanne ; Nichol, Graham. / Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART). In: Resuscitation. 2016 ; Vol. 101. pp. 57-64.
@article{8418df867dba4267b79a960ce27a9e94,
title = "Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART)",
abstract = "Airway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.",
keywords = "Airway management, Cardiopulmonary arrest, Clinical trials, Emergency medical services, Intubation (intratracheal), Resuscitation",
author = "Wang, {Henry E.} and Prince, {David K.} and Stephens, {Shannon W.} and Heather Herren and Mohamud Daya and Neal Richmond and Jestin Carlson and Craig Warden and Colella, {M. Riccardo} and Ashley Brienza and Aufderheide, {Tom P.} and Idris, {Ahamed H.} and Robert Schmicker and Susanne May and Graham Nichol",
year = "2016",
month = "4",
day = "1",
doi = "10.1016/j.resuscitation.2016.01.012",
language = "English (US)",
volume = "101",
pages = "57--64",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART)

AU - Wang, Henry E.

AU - Prince, David K.

AU - Stephens, Shannon W.

AU - Herren, Heather

AU - Daya, Mohamud

AU - Richmond, Neal

AU - Carlson, Jestin

AU - Warden, Craig

AU - Colella, M. Riccardo

AU - Brienza, Ashley

AU - Aufderheide, Tom P.

AU - Idris, Ahamed H.

AU - Schmicker, Robert

AU - May, Susanne

AU - Nichol, Graham

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Airway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.

AB - Airway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.

KW - Airway management

KW - Cardiopulmonary arrest

KW - Clinical trials

KW - Emergency medical services

KW - Intubation (intratracheal)

KW - Resuscitation

UR - http://www.scopus.com/inward/record.url?scp=84960457146&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84960457146&partnerID=8YFLogxK

U2 - 10.1016/j.resuscitation.2016.01.012

DO - 10.1016/j.resuscitation.2016.01.012

M3 - Article

C2 - 26851059

AN - SCOPUS:84960457146

VL - 101

SP - 57

EP - 64

JO - Resuscitation

JF - Resuscitation

SN - 0300-9572

ER -