Design of a small animal MR compatible PET scanner

Randal Slates, Simon Cherry, Abdel Boutefnouchet, Yiping Shao, Magnus Dahlbom, Keyvan Farahani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Using a combination of Monte-Carlo simulations and experimental measurements we have designed a small animal MR compatible PET (McPET) scanner for simultaneous PET and MR imaging of mice and rats in vivo. The scanner consists of one ring of 480 LSO crystals arranged in 3 layers with 160 crystals per layer. The crystal dimensions are 2 × 3 × 7.5 mm3. This was based on a target resolution of 2.5 mm and simulations showing that a depth of 7.5 mm was sufficient to provide this resolution across the desired field of view. The system diameter of 11.2 cm is large enough to accommodate the animal positioned inside a stereotactic frame. Each crystal will be coupled through 2 mm diameter optical fibers to multi-channel PMT's which reside outside the main magnetic field. Through 50 cm of optical fiber, a photopeak is clearly seen and the measured energy resolution is 25%. Prototype optical fiber connectors have been tested to increase the flexibility of the system and result in a light loss of only 6%. The proposed system will have adequate resolution and sensitivity for a number of applications in small animals and will be the first practical device for simultaneous in vivo imaging with PET and MR.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference
PublisherIEEE
Pages1268-1273
Number of pages6
Volume2
ISBN (Print)0780350227
StatePublished - Jan 1 1999
EventProceedings of the 1998 IEEE Nuclear Science Symposium Conference Record - Toronto, Que, Can
Duration: Nov 8 1998Nov 14 1998

Other

OtherProceedings of the 1998 IEEE Nuclear Science Symposium Conference Record
CityToronto, Que, Can
Period11/8/9811/14/98

Fingerprint

Animals
Optical fibers
Crystals
Imaging techniques
Rats
Magnetic fields

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Slates, R., Cherry, S., Boutefnouchet, A., Shao, Y., Dahlbom, M., & Farahani, K. (1999). Design of a small animal MR compatible PET scanner. In IEEE Nuclear Science Symposium and Medical Imaging Conference (Vol. 2, pp. 1268-1273). IEEE.

Design of a small animal MR compatible PET scanner. / Slates, Randal; Cherry, Simon; Boutefnouchet, Abdel; Shao, Yiping; Dahlbom, Magnus; Farahani, Keyvan.

IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 2 IEEE, 1999. p. 1268-1273.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Slates, R, Cherry, S, Boutefnouchet, A, Shao, Y, Dahlbom, M & Farahani, K 1999, Design of a small animal MR compatible PET scanner. in IEEE Nuclear Science Symposium and Medical Imaging Conference. vol. 2, IEEE, pp. 1268-1273, Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record, Toronto, Que, Can, 11/8/98.
Slates R, Cherry S, Boutefnouchet A, Shao Y, Dahlbom M, Farahani K. Design of a small animal MR compatible PET scanner. In IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 2. IEEE. 1999. p. 1268-1273
Slates, Randal ; Cherry, Simon ; Boutefnouchet, Abdel ; Shao, Yiping ; Dahlbom, Magnus ; Farahani, Keyvan. / Design of a small animal MR compatible PET scanner. IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 2 IEEE, 1999. pp. 1268-1273
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