Detection of Bladder Cancer in Urine Sediments by a Novel Multicolor Fluorescence In Situ Hybridization (Quartet) Test

Shizhen Zhang, Yan Wang, Jolanta Bondaruk, Tadeusz Majewski, Hui Yao, Sangkyou Lee, June Goo Lee, David Cogdell, Yair Lotan, Colin Dinney, Peng Wei, Keith Baggerly, Bogdan Czerniak

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We have developed a multicolored fluorescence in situ hybridization probe test comprising four probes aimed at the loci 6p22, 8q22, 11q13, and 20q11.2, which detects bladder cancer in voided urine with approximately 95% specificity and nearly 80% sensitivity.

Original languageEnglish (US)
Pages (from-to)664-675
Number of pages12
JournalEuropean Urology Focus
Volume5
Issue number4
DOIs
StatePublished - Jul 2019

Keywords

  • Bladder tumor
  • Copy number variation
  • Fluorescence in situ hybridization

ASJC Scopus subject areas

  • Urology

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