Detection of breast cancer microcalcifications using a dual-modality SPECT/ NIR fluorescent probe

Kumar R. Bhushan, Preeti Misra, Fangbing Liu, Sanjeev Mathur, Robert E. Lenkinski, John V. Frangioni

Research output: Contribution to journalShort survey

104 Scopus citations

Abstract

Efficient chemical synthesis of a trifunctional, hydroxyapatite-binding molecule, which provides simultaneous in vivo imaging by NIR fluorescence and SPECT/CT has been described. Quantitation by SPECT provides the "gold standard" by which NIR fluorescence tomography of breast cancer microcalcifications can now be compared and optimized.

Original languageEnglish (US)
Pages (from-to)17648-17649
Number of pages2
JournalJournal of the American Chemical Society
Volume130
Issue number52
DOIs
StatePublished - Dec 31 2008

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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  • Cite this

    Bhushan, K. R., Misra, P., Liu, F., Mathur, S., Lenkinski, R. E., & Frangioni, J. V. (2008). Detection of breast cancer microcalcifications using a dual-modality SPECT/ NIR fluorescent probe. Journal of the American Chemical Society, 130(52), 17648-17649. https://doi.org/10.1021/ja807099s