Detection of early tumor response to Abraxane using H-scan imaging: Preliminary results in a small animal model of breast cancer

Mawia Khairalseed, Fangyuan Xiong, Robert Mattrey, Kevin Parker, Kenneth Hoyt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Scopus citations

Abstract

H-scan is a new ultrasound (US) technique that images the relative size of acoustic scatterers. This modality relies on matching a model of pulse-echo formation to the mathematics of a class of Gaussian-weighted Hermite polynomials (GWHP). Parallel convolution filters using the second (GWH2) and eighth (GWH8) components are applied to the radio frequency US data to capture the low and high frequency signal components respectively. The relative strength from each convolution is color-coded and imaged. The purpose of this study was to evaluate the potential of H-scan imaging for characterizing tumor tissue in an animal model and any early response to systemic anticancer treatment.

Original languageEnglish (US)
Title of host publication2017 IEEE International Ultrasonics Symposium, IUS 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781538633830
DOIs
StatePublished - Oct 31 2017
Event2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States
Duration: Sep 6 2017Sep 9 2017

Other

Other2017 IEEE International Ultrasonics Symposium, IUS 2017
CountryUnited States
CityWashington
Period9/6/179/9/17

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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    Khairalseed, M., Xiong, F., Mattrey, R., Parker, K., & Hoyt, K. (2017). Detection of early tumor response to Abraxane using H-scan imaging: Preliminary results in a small animal model of breast cancer. In 2017 IEEE International Ultrasonics Symposium, IUS 2017 [8092794] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2017.8092794