Detection of group B streptococcal antigens in body fluids of neonates

J. D. Siegel, G. H. McCracken

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Considerable attention has been focused on neonatal diseases caused by the group B beta hemolytic streptococcus; early diagnosis and differentiation from other infectious and noninfectious etiologies have been stressed. There have been few reports of the use of counterimmunoelectrophoresis for identification and serotyping of group B organisms and for detection of antigen in body fluids of infants with group B streptococcal disease. We report our experience with burro type-specific antisera for groups B(Ia), B2, and B3 streptococci compared to that with a rabbit B3 antiserum and a commercially available group-specific antiserum. Antigen was detected in blood, urine, cerebrospinal fluid, pleural fluid, or cord blood of 21 infants, 20 of whom had culture proven group B streptococcal disease.

Original languageEnglish (US)
Pages (from-to)491-492
Number of pages2
JournalJournal of Pediatrics
Volume93
Issue number3
StatePublished - 1978

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Body Fluids
Immune Sera
Newborn Infant
Streptococcus
Antigens
Infant, Newborn, Diseases
Counterimmunoelectrophoresis
Serotyping
Social Identification
Fetal Blood
Cerebrospinal Fluid
Early Diagnosis
Urine
Rabbits

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Detection of group B streptococcal antigens in body fluids of neonates. / Siegel, J. D.; McCracken, G. H.

In: Journal of Pediatrics, Vol. 93, No. 3, 1978, p. 491-492.

Research output: Contribution to journalArticle

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