TY - JOUR
T1 - Detection of patent foramen ovale by Doppler color flow mapping in patients undergoing cardiac catheterization
AU - Brickner, M. Elizabeth
AU - Grayburn, Paul A.
AU - Fadel, Bahaa
AU - Carry, Melissa M.
AU - Eichhorn, Eric J.
AU - Lange, Richard A.
AU - Taylor, Anne L.
N1 - Funding Information:
From the Pulmonary Division, LDS Hospital, Salt Lake City, Utah 84143,a nd the Departmento f Medicine, University of Utah, Salt Lake City, Utah. This study was supported in part by the American Heart Association/Utah Affiliate, Salt Lake City, and the LDS Hospital-Deseret Foundation, Salt Lake City, Utah. Manuscript received September 10, 1990; revised manuscript received and accepted February 2s. 1991.
Funding Information:
From the Department of Internal Medicine (Cardiology Division), University of Texas SouthwesternM edical School and Veterans Administration Medical Center, Dallas, Texas. This study was supportedi n part by Clinical Investigator Award HL01545, National Institutes of Health, Bethesda,M aryland, the Moss Heart Fund, Dallas, Texas, and by Grant-in-Aid 886106, American Heart Association, Texas Affiliate, Austin, Texas. Manuscript received December 20, 1990; revised manuscript receiveda nd acceptedM arch 1,199l. Dr. Taylor’s address: Case Western Reserve University, University Hospitals of Cleveland, Division of Cardiology, 2074 Abington Road, Cleveland, Ohio 44106.
PY - 1991/7/1
Y1 - 1991/7/1
N2 - Autopsy studies have demonstrated that the foramen ovale is patent in 20 to 35% of the general population.1,2 Although it is generally considered to be an incidental finding, recent clinical studies suggest that the patent foramen ovale (PFO) may serve as an important route for paradoxical embolization.3,4 In addition, hypoxemia due to right-to-left shunting across a PFO may occur in the setting of elevated right heart pressures or decreased right ventricular compliance.5,6 Although contrast echocardiography has been used to identify right-to-left shunting in patients with a suspected PFO,4,7-10 this technique may be limited by its dependence on a right-to-left component of flow and by the small number of cardiac cycles in which to identify such flow. Doppler color flow mapping, which can image flow jets in either direction across an atrial septal defect, 11 also offers the potential to identify flow across a PFO. Thus, we tested the hypothesis that color flow mapping could accurately detect small jets resulting from flow across a PFO.
AB - Autopsy studies have demonstrated that the foramen ovale is patent in 20 to 35% of the general population.1,2 Although it is generally considered to be an incidental finding, recent clinical studies suggest that the patent foramen ovale (PFO) may serve as an important route for paradoxical embolization.3,4 In addition, hypoxemia due to right-to-left shunting across a PFO may occur in the setting of elevated right heart pressures or decreased right ventricular compliance.5,6 Although contrast echocardiography has been used to identify right-to-left shunting in patients with a suspected PFO,4,7-10 this technique may be limited by its dependence on a right-to-left component of flow and by the small number of cardiac cycles in which to identify such flow. Doppler color flow mapping, which can image flow jets in either direction across an atrial septal defect, 11 also offers the potential to identify flow across a PFO. Thus, we tested the hypothesis that color flow mapping could accurately detect small jets resulting from flow across a PFO.
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U2 - 10.1016/0002-9149(91)90727-3
DO - 10.1016/0002-9149(91)90727-3
M3 - Article
C2 - 2058548
AN - SCOPUS:0026346616
SN - 0002-9149
VL - 68
SP - 125
EP - 129
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 1
ER -