Determinants of Quality of Life for Patients With Kidney Stones

Karim Bensalah, Altug Tuncel, Amit Gupta, Jay D. Raman, Margaret S Pearle, Yair Lotan

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Purpose: We evaluated various factors relating to quality of life in a population of patients with stones. Materials and Methods: A total of 155 patients seen at our urology clinic for stones between January and May 2007 were prospectively questioned regarding stone history and were administered the SF-36™ questionnaire to assess quality of life. Age, body mass index, American Society of Anesthesiologists score, number of stone episodes, interval from the last stone episode, number of surgical procedures for stones and associated complications, missed days of work and long-term medical treatment were elicited from the patients. Individual SF-36 domains and composite scores were compared to those of the American general population. Univariate and multivariate regression analyses were performed to assess the impact of all covariates on quality of life scores. Results: Patients with stones scored lower than the average American population in 5 of the 8 domains of the SF-36 as well as in the physical composite score. Multivariate regression modeling showed that increasing body mass index and age were the strongest predictors of decreased physical well-being. The number of stone episodes did not influence SF-36 scores, although the number of surgical procedures impacted physical and mental components. The number of ureteroscopy procedures and stent placements primarily impacted mental well-being. Medical therapy, particularly the use of potassium citrate, was associated with more favorable quality of life. Conclusions: Various factors impact quality of life in patients with urolithiasis but the most important are body mass index, age and the number of surgical procedures. Prospective longitudinal studies may further elucidate the determinants of quality of life and they might be used to optimize patient care.

Original languageEnglish (US)
Pages (from-to)2238-2243
Number of pages6
JournalJournal of Urology
Volume179
Issue number6
DOIs
StatePublished - Jun 2008

Fingerprint

Kidney Calculi
Quality of Life
Body Mass Index
Potassium Citrate
Population
Ureteroscopy
Urolithiasis
Urology
Stents
Longitudinal Studies
Patient Care
Multivariate Analysis
History
Regression Analysis
Prospective Studies
Therapeutics

Keywords

  • body mass index
  • kidney
  • kidney calculi
  • quality of life
  • questionnaires

ASJC Scopus subject areas

  • Urology

Cite this

Determinants of Quality of Life for Patients With Kidney Stones. / Bensalah, Karim; Tuncel, Altug; Gupta, Amit; Raman, Jay D.; Pearle, Margaret S; Lotan, Yair.

In: Journal of Urology, Vol. 179, No. 6, 06.2008, p. 2238-2243.

Research output: Contribution to journalArticle

Bensalah, Karim ; Tuncel, Altug ; Gupta, Amit ; Raman, Jay D. ; Pearle, Margaret S ; Lotan, Yair. / Determinants of Quality of Life for Patients With Kidney Stones. In: Journal of Urology. 2008 ; Vol. 179, No. 6. pp. 2238-2243.
@article{e2767142dce34be8956a0c8c7fbf41e1,
title = "Determinants of Quality of Life for Patients With Kidney Stones",
abstract = "Purpose: We evaluated various factors relating to quality of life in a population of patients with stones. Materials and Methods: A total of 155 patients seen at our urology clinic for stones between January and May 2007 were prospectively questioned regarding stone history and were administered the SF-36™ questionnaire to assess quality of life. Age, body mass index, American Society of Anesthesiologists score, number of stone episodes, interval from the last stone episode, number of surgical procedures for stones and associated complications, missed days of work and long-term medical treatment were elicited from the patients. Individual SF-36 domains and composite scores were compared to those of the American general population. Univariate and multivariate regression analyses were performed to assess the impact of all covariates on quality of life scores. Results: Patients with stones scored lower than the average American population in 5 of the 8 domains of the SF-36 as well as in the physical composite score. Multivariate regression modeling showed that increasing body mass index and age were the strongest predictors of decreased physical well-being. The number of stone episodes did not influence SF-36 scores, although the number of surgical procedures impacted physical and mental components. The number of ureteroscopy procedures and stent placements primarily impacted mental well-being. Medical therapy, particularly the use of potassium citrate, was associated with more favorable quality of life. Conclusions: Various factors impact quality of life in patients with urolithiasis but the most important are body mass index, age and the number of surgical procedures. Prospective longitudinal studies may further elucidate the determinants of quality of life and they might be used to optimize patient care.",
keywords = "body mass index, kidney, kidney calculi, quality of life, questionnaires",
author = "Karim Bensalah and Altug Tuncel and Amit Gupta and Raman, {Jay D.} and Pearle, {Margaret S} and Yair Lotan",
year = "2008",
month = "6",
doi = "10.1016/j.juro.2008.01.116",
language = "English (US)",
volume = "179",
pages = "2238--2243",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - Determinants of Quality of Life for Patients With Kidney Stones

AU - Bensalah, Karim

AU - Tuncel, Altug

AU - Gupta, Amit

AU - Raman, Jay D.

AU - Pearle, Margaret S

AU - Lotan, Yair

PY - 2008/6

Y1 - 2008/6

N2 - Purpose: We evaluated various factors relating to quality of life in a population of patients with stones. Materials and Methods: A total of 155 patients seen at our urology clinic for stones between January and May 2007 were prospectively questioned regarding stone history and were administered the SF-36™ questionnaire to assess quality of life. Age, body mass index, American Society of Anesthesiologists score, number of stone episodes, interval from the last stone episode, number of surgical procedures for stones and associated complications, missed days of work and long-term medical treatment were elicited from the patients. Individual SF-36 domains and composite scores were compared to those of the American general population. Univariate and multivariate regression analyses were performed to assess the impact of all covariates on quality of life scores. Results: Patients with stones scored lower than the average American population in 5 of the 8 domains of the SF-36 as well as in the physical composite score. Multivariate regression modeling showed that increasing body mass index and age were the strongest predictors of decreased physical well-being. The number of stone episodes did not influence SF-36 scores, although the number of surgical procedures impacted physical and mental components. The number of ureteroscopy procedures and stent placements primarily impacted mental well-being. Medical therapy, particularly the use of potassium citrate, was associated with more favorable quality of life. Conclusions: Various factors impact quality of life in patients with urolithiasis but the most important are body mass index, age and the number of surgical procedures. Prospective longitudinal studies may further elucidate the determinants of quality of life and they might be used to optimize patient care.

AB - Purpose: We evaluated various factors relating to quality of life in a population of patients with stones. Materials and Methods: A total of 155 patients seen at our urology clinic for stones between January and May 2007 were prospectively questioned regarding stone history and were administered the SF-36™ questionnaire to assess quality of life. Age, body mass index, American Society of Anesthesiologists score, number of stone episodes, interval from the last stone episode, number of surgical procedures for stones and associated complications, missed days of work and long-term medical treatment were elicited from the patients. Individual SF-36 domains and composite scores were compared to those of the American general population. Univariate and multivariate regression analyses were performed to assess the impact of all covariates on quality of life scores. Results: Patients with stones scored lower than the average American population in 5 of the 8 domains of the SF-36 as well as in the physical composite score. Multivariate regression modeling showed that increasing body mass index and age were the strongest predictors of decreased physical well-being. The number of stone episodes did not influence SF-36 scores, although the number of surgical procedures impacted physical and mental components. The number of ureteroscopy procedures and stent placements primarily impacted mental well-being. Medical therapy, particularly the use of potassium citrate, was associated with more favorable quality of life. Conclusions: Various factors impact quality of life in patients with urolithiasis but the most important are body mass index, age and the number of surgical procedures. Prospective longitudinal studies may further elucidate the determinants of quality of life and they might be used to optimize patient care.

KW - body mass index

KW - kidney

KW - kidney calculi

KW - quality of life

KW - questionnaires

UR - http://www.scopus.com/inward/record.url?scp=43049119610&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43049119610&partnerID=8YFLogxK

U2 - 10.1016/j.juro.2008.01.116

DO - 10.1016/j.juro.2008.01.116

M3 - Article

C2 - 18423704

AN - SCOPUS:43049119610

VL - 179

SP - 2238

EP - 2243

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 6

ER -