Determination of stone-forming risk by measuring crystal formation in whole urine with gel model

Claus Roehrborn, Hans Joachim Schneider, Erwin W. Rugendorff

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A simple and easy-to-handle method for measuring calcium oxalate crystal formation in whole urine samples using a gel system is described. To prove reliability of the method, the crystallization-inhibiting effect of a number of well-known, so-called inhibitors of crystallization is demonstrated. In testing urine samples from recurrent stone formers and healthy controls, we found a significant difference in the inhibitor index, the stone formers producing more crystals than the controls. Experiments in test persons with oral loading of magnesium compounds and alkalinizing substances suggest that this effect is probably caused by alteration of the urine composition, e.g., a lower excretion of inhibitors by the stone formers.

Original languageEnglish (US)
Pages (from-to)531-536
Number of pages6
JournalUrology
Volume27
Issue number6
DOIs
StatePublished - 1986

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Gels
Urine
Crystallization
Magnesium Compounds
Calcium Oxalate

ASJC Scopus subject areas

  • Urology

Cite this

Determination of stone-forming risk by measuring crystal formation in whole urine with gel model. / Roehrborn, Claus; Schneider, Hans Joachim; Rugendorff, Erwin W.

In: Urology, Vol. 27, No. 6, 1986, p. 531-536.

Research output: Contribution to journalArticle

Roehrborn, Claus ; Schneider, Hans Joachim ; Rugendorff, Erwin W. / Determination of stone-forming risk by measuring crystal formation in whole urine with gel model. In: Urology. 1986 ; Vol. 27, No. 6. pp. 531-536.
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