Developing rational combinations of immune checkpoint inhibitors and radiation therapy for gastrointestinal cancers

Muhammad Shaalan Beg, Jeffrey Meyer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Evidence supporting the synergistic antitumor activity of radiation therapy combined with immune checkpoint inhibitors is rapidly growing. Investigators should consider the characteristics and challenges of gastrointestinal (GI) cancers to evaluate the safety and clinical effectiveness of this combination. In this paper, we present the rationale for exploring this strategy and the opportunities it possesses to challenge our standard of care. We also discuss unique considerations to systematically develop this combination in GI cancers.

Original languageEnglish (US)
Pages (from-to)225-230
Number of pages6
JournalJournal of Gastrointestinal Oncology
Volume9
Issue number1
DOIs
StatePublished - Feb 1 2018

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Gastrointestinal Neoplasms
Radiotherapy
Standard of Care
Research Personnel
Safety

Keywords

  • Chemoradiation
  • Gastrointestinal cancer
  • Immunotherapy
  • Radiation oncology
  • Radiation therapy

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology

Cite this

Developing rational combinations of immune checkpoint inhibitors and radiation therapy for gastrointestinal cancers. / Beg, Muhammad Shaalan; Meyer, Jeffrey.

In: Journal of Gastrointestinal Oncology, Vol. 9, No. 1, 01.02.2018, p. 225-230.

Research output: Contribution to journalArticle

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