TY - GEN
T1 - Development of a methodology for direct utilization of phase-contrast MRI in hemodynamic computations
AU - Das, Ashish
AU - Gottliebson, William M.
AU - Wansapura, Janaka
AU - Banerjee, Rupak K.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2011
Y1 - 2011
N2 - Development of non-invasive diagnostic indices often requires accurate blood-flow calculation using physiologically realistic velocity profiles as boundary conditions. In this research, a methodology is being developed and validated that can directly use phase-contrast MR imaging (PC-MRI) based velocity measurement to perform blood-flow computation with patient-specific geometry. Using this methodology, the pressure drop can also be calculated non-invasively. Although the main focus of our research has been pulmonary insufficiency (PI) in tetralogy patients, our method can be employed in many other patho-physiologies. As a pilot study, the methodology is tested using a simple model of blood-flow through a straight artery of uniform cross-section.
AB - Development of non-invasive diagnostic indices often requires accurate blood-flow calculation using physiologically realistic velocity profiles as boundary conditions. In this research, a methodology is being developed and validated that can directly use phase-contrast MR imaging (PC-MRI) based velocity measurement to perform blood-flow computation with patient-specific geometry. Using this methodology, the pressure drop can also be calculated non-invasively. Although the main focus of our research has been pulmonary insufficiency (PI) in tetralogy patients, our method can be employed in many other patho-physiologies. As a pilot study, the methodology is tested using a simple model of blood-flow through a straight artery of uniform cross-section.
UR - http://www.scopus.com/inward/record.url?scp=84881229258&partnerID=8YFLogxK
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U2 - 10.1115/SBC2011-53959
DO - 10.1115/SBC2011-53959
M3 - Conference contribution
AN - SCOPUS:84881229258
SN - 9780791854587
T3 - ASME 2011 Summer Bioengineering Conference, SBC 2011
SP - 1135
EP - 1136
BT - ASME 2011 Summer Bioengineering Conference, SBC 2011
T2 - ASME 2011 Summer Bioengineering Conference, SBC 2011
Y2 - 22 June 2011 through 25 June 2011
ER -