Development of cationic polymer coatings to regulate foreign-body responses

Minglin Ma; Wendy F. Liu; Paulina S. Hill; Kaitlin M. Bratlie; Daniel J. Siegwart; Justin Chin; Miri Park; Joao Guerreiro; Daniel G. Anderson

doi:10.1002/adma.201100513

Development of cationic polymer coatings to regulate foreign-body responses

Minglin Ma, Wendy F. Liu, Paulina S. Hill, Kaitlin M. Bratlie, Daniel J. Siegwart, Justin Chin, Miri Park, Joao Guerreiro, Daniel G. Anderson

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

A library of cationic polymers, poly(beta-amino alcohols) with a great chemical diversity are synthesized using combinatorial polymerization. These polymers, when immobilized on a surface, drastically affect the behavior of monocyte/macrophage cells in vitro and early inflammatory reactions in vivo. Certain polymers are found capable of mitigating the foreign-body responses.

Original language	English (US)
Pages (from-to)	H189-H194
Journal	Advanced Materials
Volume	23
Issue number	24
DOIs	https://doi.org/10.1002/adma.201100513
State	Published - Jun 24 2011

Keywords

biomaterials
biomedical materials
foreign-body responses
poly(beta-amino alcohol)
polymer coatings

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201100513

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title = "Development of cationic polymer coatings to regulate foreign-body responses",

abstract = "A library of cationic polymers, poly(beta-amino alcohols) with a great chemical diversity are synthesized using combinatorial polymerization. These polymers, when immobilized on a surface, drastically affect the behavior of monocyte/macrophage cells in vitro and early inflammatory reactions in vivo. Certain polymers are found capable of mitigating the foreign-body responses.",

keywords = "biomaterials, biomedical materials, foreign-body responses, poly(beta-amino alcohol), polymer coatings",

author = "Minglin Ma and Liu, {Wendy F.} and Hill, {Paulina S.} and Bratlie, {Kaitlin M.} and Siegwart, {Daniel J.} and Justin Chin and Miri Park and Joao Guerreiro and Anderson, {Daniel G.}",

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AU - Ma, Minglin

AU - Liu, Wendy F.

AU - Hill, Paulina S.

AU - Bratlie, Kaitlin M.

AU - Siegwart, Daniel J.

AU - Chin, Justin

AU - Park, Miri

AU - Guerreiro, Joao

AU - Anderson, Daniel G.

PY - 2011/6/24

Y1 - 2011/6/24

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AB - A library of cationic polymers, poly(beta-amino alcohols) with a great chemical diversity are synthesized using combinatorial polymerization. These polymers, when immobilized on a surface, drastically affect the behavior of monocyte/macrophage cells in vitro and early inflammatory reactions in vivo. Certain polymers are found capable of mitigating the foreign-body responses.

KW - biomaterials

KW - biomedical materials

KW - foreign-body responses

KW - poly(beta-amino alcohol)

KW - polymer coatings

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JF - Advanced Materials

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ER -

Development of cationic polymer coatings to regulate foreign-body responses

Abstract

Keywords

ASJC Scopus subject areas

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