Development of cationic polymer coatings to regulate foreign-body responses

Minglin Ma, Wendy F. Liu, Paulina S. Hill, Kaitlin M. Bratlie, Daniel J. Siegwart, Justin Chin, Miri Park, Joao Guerreiro, Daniel G. Anderson

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

A library of cationic polymers, poly(beta-amino alcohols) with a great chemical diversity are synthesized using combinatorial polymerization. These polymers, when immobilized on a surface, drastically affect the behavior of monocyte/macrophage cells in vitro and early inflammatory reactions in vivo. Certain polymers are found capable of mitigating the foreign-body responses.

Original languageEnglish (US)
JournalAdvanced Materials
Volume23
Issue number24
DOIs
StatePublished - Jun 24 2011

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Polymers
Coatings
Amino alcohols
Amino Alcohols
Macrophages
Polymerization

Keywords

  • biomaterials
  • biomedical materials
  • foreign-body responses
  • poly(beta-amino alcohol)
  • polymer coatings

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Ma, M., Liu, W. F., Hill, P. S., Bratlie, K. M., Siegwart, D. J., Chin, J., ... Anderson, D. G. (2011). Development of cationic polymer coatings to regulate foreign-body responses. Advanced Materials, 23(24). https://doi.org/10.1002/adma.201100513

Development of cationic polymer coatings to regulate foreign-body responses. / Ma, Minglin; Liu, Wendy F.; Hill, Paulina S.; Bratlie, Kaitlin M.; Siegwart, Daniel J.; Chin, Justin; Park, Miri; Guerreiro, Joao; Anderson, Daniel G.

In: Advanced Materials, Vol. 23, No. 24, 24.06.2011.

Research output: Contribution to journalArticle

Ma, M, Liu, WF, Hill, PS, Bratlie, KM, Siegwart, DJ, Chin, J, Park, M, Guerreiro, J & Anderson, DG 2011, 'Development of cationic polymer coatings to regulate foreign-body responses', Advanced Materials, vol. 23, no. 24. https://doi.org/10.1002/adma.201100513
Ma, Minglin ; Liu, Wendy F. ; Hill, Paulina S. ; Bratlie, Kaitlin M. ; Siegwart, Daniel J. ; Chin, Justin ; Park, Miri ; Guerreiro, Joao ; Anderson, Daniel G. / Development of cationic polymer coatings to regulate foreign-body responses. In: Advanced Materials. 2011 ; Vol. 23, No. 24.
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